Consolidated microbial production of four-, five-, and six-carbon organic acids from crop residues: Current status and perspectives

Integrated Biorefinery Design with Techno‐Economic and Life Cycle Assessment Tools in Polyhydroxyalkanoates Processing

“…The consolidated bioprocessing approach, which combines biomass pretreatment with saccharification and fermentation is more beneficial for the production of PHAs and other value-added products. [51] The realization of the circular economy approach in PHAs production recently become a hot topic in research. [37,130] If lignocellulosic biorefinery uses the advanced and green technologies mentioned above, it can help to mitigate the global environmental challenges due to the excessive use and production of fossil-based products.…”

“…[50] On the other hand, the CBP approach combines pretreatment with saccharification and fermentation in a single step, thus reducing the costs invest in multiple processes. [49,51] Previous technoeconomic assessments demonstrate that the implementation of CBP approaches in the biorefinery reduces 20% to 40% of costs as compared to conventional approaches. [56] Thus, the CBP approach is receiving much attention from the researcher as compared to the SSF approach.…”

“…CBP approach includes either i) a genetically engineered strain to express and secret biomass hydrolyzing enzymes to convert it into fermentable sugars for the biosynthesis of desired products, ii) constructing desired products' metabolic pathways into the microbes that natively degrade biomass, or iii) integrating both approaches. [51,57] Salamanca-Cardona et al [58] Escherichia coli JW0885 strain was engineered to overexpress xylanases and PHA-producing enzymes for the biosynthesis of poly(lactate-co-3-hydroxybutyrate) P[LA-co-3HB] from beechwood xylan as a consolidated bioprocessing strategy. Likewise, Salvachúa et al [54] demonstrated the simultaneous depolymerization of lignin and catabolism of aromatic derivatives from lignin in bacteria to accumulate mcl-PHAs, as shown in Figure 4.…”

Isolation of Spoiling Micromycetes in Lignocellulosic Residues of Cereal Crops

“…Mass burning of crop residues in the fields leads to environmental degradation and the loss of valuable resources. In world practice, there are various directions for the use of lignocellulosic agricultural wastes, including biofuel production [3][4][5][6], composting [7][8][9], use as a biofertilizer for promoting plant growth, and improving soil structure [10,11], and the production of valuable compounds [12][13][14]. The search for new ways and work to improve the economic efficiency of using lignocellulosic waste to produce high-valueadded products is constantly ongoing.…”

“…Массовое сжигание пожнивных остатков на полях приводит к ухудшению экологической ситуации и потере ценных ресурсов. В мировой практике существуют различные направления использования лигноцеллюлозных отходов сельскохозяйственных культур, включая получение биотоплива [3][4][5][6], компостирование [7][8][9], применение в качестве биоудобрения для стимуляции роста растений и улучшения структуры почвы [10,11], продукцию ценных соединений [12][13][14]. Постоянно продолжается поиск новых способов и работа над повышением экономической эффективности использования лигноцеллюлозных отходов для получения продуктов с высокой добавленной стоимостью.…”