Considerations in Treating Severe Acne With Isotretinoin in Transgender Men

Richer, Vincent; Kuritzky, Louis

doi:10.1177/1203475420930224

Cited by 7 publications

(7 citation statements)

References 6 publications

(8 reference statements)

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“…135 Richer et al have recommended respectfully addressing reproductive status, anatomy, and sexual practices to gauge pregnancy risk, guide counselling, and provide the best care for these patients. 136 For example, it is important to consider that a transgender man may no longer have a uterus or may engage in sexual activities with individuals who do not have a penis and/or testes with reproductive potential. 136 Previously, the iPLEDGE program (United States of America) required clinicians to categorize patients as either: male, female of nonchildbearing potential, or female of childbearing potential and only the latter had to undergo strict pregnancy monitoring.…”

Section: -320mentioning

confidence: 99%

“…136 For example, it is important to consider that a transgender man may no longer have a uterus or may engage in sexual activities with individuals who do not have a penis and/or testes with reproductive potential. 136 Previously, the iPLEDGE program (United States of America) required clinicians to categorize patients as either: male, female of nonchildbearing potential, or female of childbearing potential and only the latter had to undergo strict pregnancy monitoring. This classification system posed a significant dilemma for patients and clinicians who had to either categorize the patient according to their assigned sex at birth (and neglect the patient’s identity) or based on their gender identity (which did not respect prior iPLEDGE principles).…”

Section: Part 3 – Dermatology In the Transgender Populationmentioning

confidence: 99%

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The Role of Sex and Gender in Dermatology - From Pathogenesis to Clinical Implications

et al. 2023

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Background Sex and gender have increasingly been recognized as significant risk factors for many diseases, including dermatological conditions. Historically, sex and gender have often been grouped together as a single risk factor in the scientific literature. However, both may have a distinct impact on disease incidence, prevalence, clinical presentation, severity, therapeutic response, and associated psychological distress. Objectives and project description The mechanisms that underlie differences in skin diseases between males, females, men, and women remain largely unknown. The specific objectives of this review paper are: To highlight the biological differences between males and females (sex), as well as the sociocultural differences between men and women (gender) and how they impact the integumentary system. To perform a literature review to identify important sex- and gender-related epidemiological and clinical differences for various skin conditions belonging to a range of disease categories and to discuss possible biological and sociocultural factors that could explain the observed differences. To discuss dermatological skin conditions and gender-affirming treatments within the transgender community, a population of individuals who have a gender identity which is different than the gender identity they were assigned at birth. Future impact With the rising number of individuals that identify as non-binary or transgender within our increasingly diverse communities, it is imperative to recognize gender identity, gender, and sex as distinct entities. By doing so, clinicians will be able to better risk-stratify their patients and select treatments that are most aligned with their values. To our knowledge, very few studies have separated sex and gender as two distinct risk factors within the dermatology literature. Our article also has the potential to help guide future prevention strategies that are patient-tailored rather than using a universal approach.

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Section: -320mentioning

confidence: 99%

Section: Part 3 – Dermatology In the Transgender Populationmentioning

confidence: 99%

The Role of Sex and Gender in Dermatology - From Pathogenesis to Clinical Implications

et al. 2023

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“…I read with interest the article by Richter and Kuritzky discussing considerations in treating severe acne with Isotretinoin in transgender men. 1 Although the authors state that " Trans men with native internal female reproductive organs have a risk of gestation that is difficult to quantify despite possibly finding themselves amenorrheic due to testosterone treatment," what is not specifically stated is that transgender men with a retained functional uterus and ovaries have become pregnant, both during and after testosterone therapy. 2 In a web-based survey from 2014, amongst 25 transgender men reporting using testosterone before pregnancy, 5 (20%) reported conceiving while still amenorrheic from testosterone use.…”

Section: Reader Comment Regarding "Considerations In Treating Severe ...mentioning

confidence: 99%

“…I read with interest the article by Richter and Kuritzky discussing considerations in treating severe acne with Isotretinoin in transgender men. 1…”

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Reader Comment Regarding “Considerations in Treating Severe Acne With Isotretinoin in Transgender Men”

Haber

2021

J Cutan Med Surg

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“…We thank Dr Haber for his interest in and response to our article 1 on the topic of isotretinoin use in transgender men. Furthermore, we thank him for bringing additional awareness of this underserved population to our scientific and professional community.…”

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confidence: 99%

Response to Reader Comment on “Considerations in Treating Severe Acne With Isotretinoin in Transgender Men”

Kuritzky

Richer

2021

J Cutan Med Surg

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Considerations in Treating Severe Acne With Isotretinoin in Transgender Men

Cited by 7 publications

References 6 publications

The Role of Sex and Gender in Dermatology - From Pathogenesis to Clinical Implications

The Role of Sex and Gender in Dermatology - From Pathogenesis to Clinical Implications

Reader Comment Regarding “Considerations in Treating Severe Acne With Isotretinoin in Transgender Men”

Response to Reader Comment on “Considerations in Treating Severe Acne With Isotretinoin in Transgender Men”

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