2020
DOI: 10.1021/acs.est.0c04892
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Considerations for Prioritization of Polycyclic Aromatic Compounds as Environmental Contaminants

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Cited by 27 publications
(22 citation statements)
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“…PAHs are widespread organic pollutants. [1][2][3][4][5] PAHs lead to negative effects on the environment; they have carcinogenic and mutagenic properties affecting highly human beings as well as the aquatic system. In addition, PAHs constitute the largest group of chemical compounds known to cause cancer.…”
Section: Introductionmentioning
confidence: 99%
“…PAHs are widespread organic pollutants. [1][2][3][4][5] PAHs lead to negative effects on the environment; they have carcinogenic and mutagenic properties affecting highly human beings as well as the aquatic system. In addition, PAHs constitute the largest group of chemical compounds known to cause cancer.…”
Section: Introductionmentioning
confidence: 99%
“…Due to their negative impacts on both human and wildlife health, a subset of PACs are listed as Schedule 1 toxic substances under the Canadian Environmental Protection Act (CEPA) 1999 and as priority contaminants by the United States Environmental Protection Agency (USEPA) ( Abdel-Shafy & Mansour, 2016 ; Government of Canada, 2013 ; Keith, 2015 ). However, there is increasing concern that this list of priority contaminants should be expanded beyond the traditional parent compounds to include current, environmentally relevant PACs such as alkylated and heterocyclic derivatives ( Marvin et al, 2020 ).…”
Section: Introductionmentioning
confidence: 99%
“…While previous reviews have summarized the effects of different EDCs on female reproductive health and the ovary ( Bolden et al, 2017 , Hannon and Flaws, 2015 , Lauretta et al, 2019 , Patel et al, 2015 , Rattan et al, 2017 ), evidence regarding the effects of PAC exposure on mammalian ovarian function is limited. Toxicological studies investigating the endocrine disruptive effects of PACs focus largely on parent PAH compounds and overlooks other classes that are also present in the environment and may be more toxic than their parent/unsubstituted compounds ( Hsieh et al, 2021 , Lam et al, 2018 ; Lee et al, 2017 , Marvin et al, 2020 , Provencher et al, 2020 ). As such, there is an urgent need to consider PACs as a priority environmental contaminant, especially as the risk for exposure continues to grow in parallel with urban/industrial expansion and the global reliance for petroleum products ( Marvin et al, 2020 ).…”
Section: Introductionmentioning
confidence: 99%
“…Polycyclic aromatic hydrocarbons (PAHs) are among the most abundant contaminants in the environment. Several of these PAHs have been listed as priority pollutants to be eliminated from water, soil, or sediments because of their toxicity and/or their carcinogenic activity ( 1 4 ).…”
Section: Introductionmentioning
confidence: 99%