Conservative versus Liberal Oxygen Therapy

Oxygenation target in acute respiratory distress syndrome

“…The inclusion of patients with different diagnoses, lung injuries, and clinical parameters precluded the drawing of definite conclusions on specific subgroups. [ 74 ] Among the seven RCTs that compared different oxygenation targets in the general ICU population, [ [68] , [69] , [70] , [71] , [72] , [73] , 75 ] three [ 68 , 70 , 75 ] have published results from the subgroup of septic patients. [ [76] , [77] , [78] ] Notably, patients with cardiac arrest and ischemic hypoxic encephalopathy comprised more than 10% of the population in some studies, [ 68 ] and approximately 40% of patients in the ICU-ROX trial had acute brain disease.…”