Conservative treatment options for carpal tunnel syndrome: a systematic review of randomised controlled trials

Gerritsen, Annette; Krom, M.C.T.F.M. de; Struijs, Margaretha A.; Scholten, R. J. P. M.; Vet, Henrica C.W. de; Bouter, Lex M.

doi:10.1007/s004150200004

Cited by 185 publications

(142 citation statements)

References 38 publications

Supporting

Mentioning

122

Contrasting

Unclassified

Order By: Relevance

“…Exclusion criteria were: 1) prior treatment with wrist splint or carpal tunnel release surgery; 2) history of median nerve injury from trauma; 3) current pregnancy; 4) history of diabetes mellitus; 5) clinical signs of cervical radiculopathy; or 6) severe thenar muscle atrophy. 10 After inclusion and exclusion criteria were met, each participant received an explanation of the study and signed a written consent form prior to their participation.…”

Section: Methodsmentioning

confidence: 99%

“…10 A Cochrane database review on nonsurgical versus surgical treatments for CTS concluded surgery was the better approach, however, wrist splinting was the only non-surgical treatment included in the review. 11 Napadow et al 12 had 6 CTS patients undergo 5 weeks of acupuncture and evaluated changes in functional MRI, nerve conduction and Boston Questionnaire (BQ) scores.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The effects of active release technique on carpal tunnel patients: A pilot study

George

Tepe

Busold³

et al. 2006

Journal of Chiropractic Medicine

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The effects of active release technique on carpal tunnel patients: A pilot study

George

Tepe

Busold³

et al. 2006

Journal of Chiropractic Medicine

View full text Add to dashboard Cite

show abstract

“…Median sinir duyu ve mikst iletim çalışmalarında bileşik duyu aksiyon potansiyeli (BDAP) amplitüd normal, iletim hızı yavaşlamasının saptanması hafif derecede KTS, bu bulgulara median sinir motor iletim çalışmasında DML uzamasının eşlik etmesi ile orta derecede KTS, duyu iletim çalışmalarında BDAP potansiyel saptanamaması, amplitüdünde azalma saptanması ve/veya motor iletim çalışmasında bileşik kas aksiyon potansiyeli (BKAP) amplitüdü azalması ağır derecede KTS olarak yorumlanmaktadır 2,8 , Bu araştırmada BDAP amplitüd (mV), pik duyu iletim hızı (m/sn), mikst iletim hızı (m/sn), BKAP amplitüd (mV), DML (msn) ve ön kol iletim hızı (m/sn) değerlendirmeye alındı. İstatistiksel analiz; Windows için SPSS sürüm 12,0 (SPSS Inc, Chicago, İL, ABD) kullanıldı.…”

Section: Materyal Ve Metotunclassified

“…Bu araştırmanın amacı elektrofizyolojik olarak KTS tanısı almış hastaların tedavilerinde kullanılan steroid iyontoforezi, steroid fonoforezi lokal kortikosteroid enjeksiyonu ve NSAII kullanımının semptom, 2,3 . Konservatif tedavi yetersizse veya motor güçsüzlük ve tenar atrofi varsa cerrahi endikedir 1 .…”

Section: Introductionunclassified

Comparison of Corticosteroid Injection, Fonoforesis and Iontoforesis in Carpal Tunnel Syndrome

Karayol¹,

Ünlü²,

Çakici³

2017

Kafkas J Med Sci

View full text Add to dashboard Cite

show abstract

“…First we show, however, that meta-analysis was impeded by these problems in 2 systematic reviews concerning conservative and surgical treatment options for CTS. 7,8 …”

mentioning

confidence: 99%

Enabling meta-analysis in systematic reviews on carpal tunnel syndrome

Gerritsen

Vet

Scholten

et al. 2002

The Journal of Hand Surgery

Self Cite

View full text Add to dashboard Cite

Possible solutions to the problems of clinical heterogeneity of outcome measures and inadequate reporting of results for randomized controlled trials (RCTs) on carpal tunnel syndrome (CTS) are presented. Meta-analysis was impeded by these problems in 2 systematic reviews concerning conservative and surgical treatment options for CTS. A solution to the problem of inadequate data presentation is to add explicit information on minimal requirements with regard to data presentation to guidelines for the reporting of studies. To resolve the problem of clinical heterogeneity of the outcomes there should be consensus on the (validated) outcomes that should be used in RCTs. For CTS there is little evidence available on the reliability, validity, and responsiveness to change of the commonly used outcomes in RCTs.Resolving both problems will increase the comparability of RCTs, enabling the calculation of a pooled estimate of effect in a meta-analysis. Systematic reviews of high-quality, randomized controlled trials (RCTs) are considered to be the highest level of evidence in research concerning medical interventions. 1 To quantify the effect of the various treatment options, preferably a meta-analysis is performed. By combining individual study results a precise estimate of the magnitude of the treatment effect can be obtained. Meta-analysis is, therefore, an important part of a systematic review. Meta-analysis is only feasible if RCTs are clinically homogeneous, that is, if the patients, interventions, comparisons, outcomes, and timing of follow-up measurements are sufficiently similar. 2 Randomized controlled trials, however, may use a range of different outcome measures. 3,4 Another prerequisite for combining study results is adequate and uniform data presentation. Reporting of results in biomedical journals is often inadequate. 5,6 This article presents possible solutions to the problems of clinical heterogeneity of the outcome measures and inadequate reporting of results for RCTs on carpal tunnel syndrome (CTS). First we show, however, that meta-analysis was impeded by these problems in 2 systematic reviews concerning conservative and surgical treatment options for CTS. 7,8

show abstract

Conservative treatment options for carpal tunnel syndrome: a systematic review of randomised controlled trials

Cited by 185 publications

References 38 publications

The effects of active release technique on carpal tunnel patients: A pilot study

The effects of active release technique on carpal tunnel patients: A pilot study

Comparison of Corticosteroid Injection, Fonoforesis and Iontoforesis in Carpal Tunnel Syndrome

Enabling meta-analysis in systematic reviews on carpal tunnel syndrome

Contact Info

Product

Resources

About