Conservative Management of Thrombosed Vein of Galen Malformations

Zampella, Edward; Aronin, Patricia A.; Odrezin, Gregory T.; Duvall, Ernest R.

doi:10.1159/000120402

Cited by 4 publications

(2 citation statements)

References 3 publications

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“…There have been no reports of recanalization in the literature. 7,9,11,[13][14][15]18,19,21 There are competing strategies treatment of VGM and subsequent hydrocephalus. Embolization not only allows the removal of the high venous pressure to improve reabsorption of cerebrospinal fluid, but also over time decreases the size of the malformation allowing for improvement of hydrocephalus due to compression of cerebral aqueduct.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Occlusion of a Vein of Galen Malformation: A Case Report and Proposed Mechanism

Storey

Notarianni

Nanda

et al. 2016

J Pediatr Neuroradiol

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A vein of Galen malformation (VGM) is a rare condition of the pediatric population. Our patient was diagnosed with VGM on intrauterine ultrasound. At birth, she was noted to have multiple congenital heart defects but no signs of congestive heart failure, and intervention was delayed. Our patient presented at 4 months of age with worsening hydrocephalus due to the enlargement of the VGM. A ventricular peritoneal shunt was placed. At 26 months of age, our patient was taken for embolization of the VGM. Cerebral angiography showed no VGM. We present that changes in hemodynamics after shunt placement lead to the thrombosis of the VGM.

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Section: Discussionmentioning

confidence: 99%

Spontaneous Occlusion of a Vein of Galen Malformation: A Case Report and Proposed Mechanism

Storey

Notarianni

Nanda

et al. 2016

J Pediatr Neuroradiol

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“…In the 245 cases reported by JOHNSTON (1987), in the 43 cases of ZERAH (1992), and from a literature review (AL WATBAN 1987;CIR-ICILLO 1990;CRAWFORD 1990;MAHEUT 1987;MAY-BERG 1988;O'DONNABHAIN 1989;WISOFF 1990;ZAMPELLA 1988), the incidence of hydrocephalus is 46.8%. In the 245 cases reported by JOHNSTON (1987), in the 43 cases of ZERAH (1992), and from a literature review (AL WATBAN 1987;CIR-ICILLO 1990;CRAWFORD 1990;MAHEUT 1987;MAY-BERG 1988;O'DONNABHAIN 1989;WISOFF 1990;ZAMPELLA 1988), the incidence of hydrocephalus is 46.8%.…”

Section: -Hydrocephalusmentioning

confidence: 99%

Neonatal and Fetal Brain Malformations

Couture

2001

Medical Radiology

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Hydrodynamics in vein of Galen malformations

et al. 1992

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Forty-three patients with vein of Galen aneurysmal malformations (VGAM) referred to us for endovascular treatment between 1985 and 1990 and 335 additional cases published in the literature were reviewed with particular attention to the presence of ventricular enlargement and outcome after shunting. Hydrocephalus was the second most frequent symptom (46.8%); it is more frequent in infants (73%) than in children, adults (30%) or neonates (15%). Of the patients reported in the literature, 17.9% had undergone shunting. Within the shunted population there was an overall morbidity of 41% and a mortality of 10% (especially in the infant group). In our series 17 patients (39.5%) were shunted and a significant difference in the clinical outcome was noted between the shunted and the nonshunted group. Of the nonshunted patients, 66.6% were free of any neurological deficit or mental retardation and fewer than 5% presented with significant mental retardation. On the other hand, only 33.3% of the shunted patients had a favorable outcome and more than 15% developed significant mental retardation. Among the various causes of hydrocephalus in patients with VGAMs, such as obstruction of the aqueduct, subarachnoid hemorrhage, or ex vacuo hydrocephalus, high venous pressure may be of particular importance. In this article a physiopathological interpretation of the hydrodynamics in VGAMs is developed and a speculative explanation for CSF disorders related to ventricular shunting proposed. Treatment of hydrocephalus in VGAMs can be achieved through obliteration of the malformation or at least diminishing the venous pressure; surgical ventricular shunting does not have to be the first treatment of hydrodynamic disorders associated with VGAMs, especially in infants.

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Conservative Management of Thrombosed Vein of Galen Malformations

Cited by 4 publications

References 3 publications

Spontaneous Occlusion of a Vein of Galen Malformation: A Case Report and Proposed Mechanism

Spontaneous Occlusion of a Vein of Galen Malformation: A Case Report and Proposed Mechanism

Neonatal and Fetal Brain Malformations

Hydrodynamics in vein of Galen malformations

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