“…2 Neonatal survival is poor in most previable preterm PROM case series, but there is great variation among reports with survival rates ranging from 12% to 92%. 3,4 Persistent oligohydramnios is associated with lower survival. In addition, patients with previable preterm PROM show a higher incidence of neonatal morbidity than preterm neonates born at the same gestational age without preterm PROM.…”
“…2 Neonatal survival is poor in most previable preterm PROM case series, but there is great variation among reports with survival rates ranging from 12% to 92%. 3,4 Persistent oligohydramnios is associated with lower survival. In addition, patients with previable preterm PROM show a higher incidence of neonatal morbidity than preterm neonates born at the same gestational age without preterm PROM.…”
“…Neonatal survival is poor in most case series, but with great variation among reports, from 12 to 92% [2,3]. This wide range of reported survival rates depends on the gestational age at which membranes ruptured, and is possibly inXuenced by biased reports.…”
Perinatal mortality is high in pregnancies complicated by previable rupture of membranes, however gestational age at occurrence is a strong predictor of outcome. An individualized approach is the best management option regarding maternal risks and fetal outcomes.
“…The length of the latency period (time between PPROM and delivery) and the gestational age (g.a.) at birth are the most important prognostic factors for neonatal survival without sequelae, specially in cases of very preterm onset [8][9][10]. Therefore, the prolongation of the latency period must be considered as a priority in the expectant management of PPROM.…”
The upward trend in the duration of latency period in all groups over the years of study and the encouraging perinatal survival observed, even in previable PPROM, are incentives to follow expectant/conservative management in these cases.
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