Conservative Management of Positive Axilla After Neoadjuvant Systemic Therapy—The Need for, and Review of, Techniques Used for Lymph Node Localization

Green, Matthew; Neamonitou, Foteini; Vidya, Raghavan

doi:10.1016/j.clbc.2018.06.001

Cited by 6 publications

(2 citation statements)

References 21 publications

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“…Each of the above methods improves effectiveness of SLNB. However, depending on the centre, its technical and financial capabilities, different node marking techniques are used [84]. Attaching the marker to the metastatic lymph node before the start of NAT, analogically to the breast tumour, allows precise labelling of the lymph node containing metastasis.…”

Section: Initially Cn1 Lymph Nodesmentioning

confidence: 99%

Leczenie przedoperacyjne chorych na raka piersi i jego wpływ na postępowanie operacyjne oraz radioterapeutyczne (część 2.)

Nowecki

Jagiełło-Gruszfeld

Pogoda

et al. 2021

Nowotwory. Journal of Oncology

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Neoadjuvant therapy (NAT) is increasingly applied in patients with initially inoperable breast cancers and, frequently, in those with tumours that are initially operable, too. In most cases, the response to the applied NAT affects the scope of surgical treatment and radiotherapy, and in some situations also the complementary systemic postoperative treatment. The available studies indicate importance of response to NAT within the breast and regional lymph nodes. Assessment of response to treatment allows personalization of treatment and in some cases a change of therapy, which improves long-term outcomes. This article summarizes the current rules of conduct in patients with early breast cancer qualified for neoadjuvant therapy, paying attention to the practical aspects and possibilities of national health insurance-covered therapies in Poland. It discusses in detail the applied regimens of systemic therapy, surgical techniques, eligibility rules and complementary radiotherapy. Systems for assessing response to neoadjuvant treatment are also presented.

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Section: Initially Cn1 Lymph Nodesmentioning

confidence: 99%

Leczenie przedoperacyjne chorych na raka piersi i jego wpływ na postępowanie operacyjne oraz radioterapeutyczne (część 2.)

Nowecki

Jagiełło-Gruszfeld

Pogoda

et al. 2021

Nowotwory. Journal of Oncology

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“…The radioactive tracer-based method involves intra- and subdermal injection at the skin margins overlying the tumor of Tc-99m-labeled nanocolloidal albumin before surgery, followed by a preoperative lymphoscintigram obtained hours after tracer administration. A gamma probe identifies radioactivity in the draining ALNs during surgery [ 8 ]. If blue dye is used, blue-stained lymphatic channels visualized during surgery are followed to LNs where the blue dye accumulates [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Image-Guided Localization Techniques for Metastatic Axillary Lymph Nodes in Breast Cancer; What Radiologists Should Know

Paola¹,

Mazzotta

Conti

et al. 2023

Cancers

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Targeted axillary dissection (TAD) is an axillary staging technique after NACT that involves the removal of biopsy-proven metastatic lymph nodes in addition to sentinel lymph node biopsy (SLNB). This technique avoids the morbidity of traditional axillary lymph node dissection and has shown a lower false-negative rate than SLNB alone. Therefore, marking positive axillary lymph nodes before NACT is critical in order to locate and remove them in the subsequent surgery. Current localization methods include clip placement with intraoperative ultrasound, carbon-suspension liquids, localization wires, radioactive tracer-based localizers, magnetic seeds, radar reflectors, and radiofrequency identification devices. The aim of this paper is to illustrate the management of axillary lymph nodes based on current guidelines and explain the features of axillary lymph node markers, with relative advantages and disadvantages.

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Early reflector localization improves the accuracy of localization and excision of a previously positive axillary lymph node following neoadjuvant chemotherapy in patients with breast cancer

Balija

Braz

Hyman

et al. 2021

Breast Cancer Res Treat

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Conservative Management of Positive Axilla After Neoadjuvant Systemic Therapy—The Need for, and Review of, Techniques Used for Lymph Node Localization

Cited by 6 publications

References 21 publications

Leczenie przedoperacyjne chorych na raka piersi i jego wpływ na postępowanie operacyjne oraz radioterapeutyczne (część 2.)

Leczenie przedoperacyjne chorych na raka piersi i jego wpływ na postępowanie operacyjne oraz radioterapeutyczne (część 2.)

Image-Guided Localization Techniques for Metastatic Axillary Lymph Nodes in Breast Cancer; What Radiologists Should Know

Early reflector localization improves the accuracy of localization and excision of a previously positive axillary lymph node following neoadjuvant chemotherapy in patients with breast cancer

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