Conservative management of congenital dacryocystocele: resolution and complications

Lee, Min Joung; Park, Jinku; Kim, Namju; Choung, Ho Kyung; Khwarg, Sang In

doi:10.1016/j.jcjo.2018.08.006

Cited by 7 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We explain these results by the systematic eye washing and lacrimal sac massage, newly introduced in the Department of Neonatology at the University Children's Hospital, Bern, Switzerland, as part of this study. The massage of the lacrimal sac has been recognized as a very efficient therapy (17), and is recommended as the first-line treatment in CNLDO (18,19).…”

Section: Resultsmentioning

confidence: 99%

Euphrasia Eye Drops in Preterm Neonates With Ocular Discharge: A Randomized Double-Blind Placebo-Controlled Trial

et al. 2020

View full text Add to dashboard Cite

Aim: To investigate whether the early administration of Euphrasia eye drops ® in preterm neonates presenting with ocular discharge fosters the resolution of the ocular discharge and reduces the need for topical antibiotic therapy, as compared to placebo. Methods: We conducted a randomized double-blind placebo-controlled trial at the University Children's Hospital Bern, Switzerland. Preterm neonates with white, yellow, or green ocular discharge were included. Infants were randomly assigned (1:1) to the Euphrasia arm (Euphrasia eye drops ® , Weleda AG, Arlesheim) or the placebo arm (NaCl 0.9%). Euphrasia or placebo was administrated at a dose of one drop in each eye four times a day over a period of 96 h. The primary outcome was the treatment success, defined as no ocular discharge at 96 h and no use of topical antibiotic therapy during the 96-h intervention. Results: A total of 114 neonates were screened and 84 were randomized. Among neonates in the Euphrasia arm, 22 (55.0%) achieved our primary outcome compared to 21 (51.2%) in the placebo arm (p = 0.85). In the Euphrasia arm, time to resolution of reddening tended to fall within the shorter bracket of 24 to 48 h (24 (92.3%) vs. 12 (80.0%) in the placebo arm, p = 0.34) and relapse or first signs of reddening during the 96-h intervention tended to be lower [3 (7.9%) eyes vs. 8 (18.2%) eyes in the placebo arm, p = 0.17]. Tearing at 96 h tended to be lower in the Euphrasia arm [5 (12.8%) eyes in the Euphrasia arm vs. 12 (27.3%) eyes in the placebo arm, p = 0.10]. Discussion: Euphrasia did not significantly improve treatment success, defined as no ocular discharge at 96 h and no use of topical antibiotic therapy during the 96-h intervention. However, results suggest that Euphrasia may be of benefit for symptoms such as reddening and tearing, and thus improve the comfort of patients. Trial Registration: The trial is registered at the US National Institutes of Health (ClinicalTrials.gov) NCT04122300 and at the portal for human research in Switzerland SNCTP000003490.

show abstract

Section: Resultsmentioning

confidence: 99%

Euphrasia Eye Drops in Preterm Neonates With Ocular Discharge: A Randomized Double-Blind Placebo-Controlled Trial

et al. 2020

View full text Add to dashboard Cite

show abstract

“…3,9 Different results are reported in the literature regarding treatment approaches. Lee and colleagues 21 stated that most (74.1%) uninfected CDC can be resolved by conservative management; lacrimal probing was needed in only five (18.5%) persistent cases. Schnall and Christian 18 reported a 76% improvement and opening of the obstruction after 6 days of medical treatment in non-infected dacryocystocele; the remaining 24% were reported as persistent obstructions, and probing surgery was required despite 2 weeks of treatment.…”

Section: Discussionmentioning

confidence: 99%

Outcomes of lacrimal probing surgery as the first option in the treatment of congenital dacryocystocele

et al. 2021

View full text Add to dashboard Cite

Purpose: To determine the demographic and clinical characteristics of newborn patients who underwent lacrimal probing surgical intervention with or without the marsupialization of intranasal cysts as the primary management for dacryocystocele treatment. Methods: Data from the medical charts of 350 infants who underwent lacrimal probing surgery due to nasolacrimal duct obstruction were reviewed retrospectively. Ten newborn patients with a naive diagnosis of congenital dacryocystocele were included in the study. Congenital dacryocystocele diagnosis was based on a triad of swelling in the inner canthal region, a bluish appearance, and epiphora. Lacrimal probing surgery accompanied by nasal endoscopy was planned for all patients as the first treatment option. Results: The mean age of the patients was 24.90 ± 7.15 days, with a range of 6–85 days. A total of 10 patients were included, comprising seven females and three males. The mean postoperative follow-up period was 38.7 ± 24.41 months. Five patients had left, four patients had right, and one patient had bilateral dacryocystocele. Seven eyes of the six patients had uncomplicated dacryocystocele, while the remaining patients had dacryocystocele with complications of dacryocystitis and/or preseptal cellulitis. All patients had intranasal cysts. All patients underwent one session of lacrimal probing surgery under general anesthesia; all with successful outcomes. Four patients with additional dacryocystocele-associated complications underwent combined intranasal marsupialization of the cyst wall. Discussion: Lacrimal probing surgery ± intranasal marsupialization of the cyst wall as a first treatment option can be effective for both congenital dacryocystocele and/or congenital dacryocystocele plus associated complications and provide complete resolution of dacryocystocele-related symptoms.

show abstract

Neonatal nasal obstruction

Villarroel

Sedano

2021

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

Conservative management of congenital dacryocystocele: resolution and complications

Cited by 7 publications

References 15 publications

Euphrasia Eye Drops in Preterm Neonates With Ocular Discharge: A Randomized Double-Blind Placebo-Controlled Trial

Euphrasia Eye Drops in Preterm Neonates With Ocular Discharge: A Randomized Double-Blind Placebo-Controlled Trial

Outcomes of lacrimal probing surgery as the first option in the treatment of congenital dacryocystocele

Neonatal nasal obstruction

Contact Info

Product

Resources

About