We present an evidence of isospin effects in nuclear fission by comparing the fission widths for reactions involving different isospin states of the same compound nucleus (CN). Yadrovsky [1] suggested this possibility in 1975. Yadrovsky obtained the fission widths for two reaction data sets, namely 206 Pb(α,f) and 209 Bi(p,f), both leading to same CN, and concluded that "a nucleus remembers the isospin value of the nuclear states leading to fission". We obtain the fission decay widths for both the T 0 + 1 2 and T 0 − 1 2 states of CN by using two appropriate reaction data sets. We then compare the fission widths for the two isospin states of CN. More specifically, we have chosen the combination of 206 Pb(α,f) and 209 Bi(p,f) same as presented in Yadrovsky's paper [1] in this study. A significant difference between the ratios of fission decay widths to total decay widths for different isospin values suggests that isospin plays an important role in fission.