“…The reality of the significant influence of gravity (the hydrostatic effect) on hemodynamics in humans, as an upright creature, has already been demonstrated [ 6 , 9 , 26 , 33 , 37 , 38 ] (Fig. 2 ).…”
Section: Physiological Antropology Of Cardiovascular Adaptation To the Earth’s Gravitymentioning
confidence: 99%
“…Figure 5 clearly presents that the share of hyperkinetic (type III) hemodynamic reaction to the change of the influence of gravity clearly increases during the reproductive age and, especially, during the post-reproductive age. At the same time, this transition is enhanced by comorbid conditions, especially by the presence of arterial hypertension in both humans and monkeys, as representatives of the same order of primates [ 6 , 11 , 20 , 21 , 23 , 27 , 28 , 39 – 42 ]. Fig.…”
Section: Physiological Antropology Of Cardiovascular Adaptation To the Earth’s Gravitymentioning
confidence: 99%
“…Therefore, the “anthropogenic model” is considered not only as a step-by-step ontogenetic formation of upright walking, which is the main postural and motor form of human activity as an upright being, but also as a permanent organizational adaptation to Earth’s gravity in all of its physiological and pathological manifestations [ 3 , 4 , 6 , 8 , 29 , 37 , 49 , 52 – 54 ].…”
Section: Changes In the Cardiovascular System During Postnatal Ontogenesis As An Anthropogenic Basis For The Physiology And Pathology Of mentioning
confidence: 99%
“…This is due to a violation of the daily rhythm with an increase in the time spent in a vertical position with a shortening of the lying period, including violations of the natural synchronization of the “day-night” biorhythm. The abovementioned factors result in an increase in the body’s tension in the anti-gravity mode [ 1 – 4 , 6 , 29 , 32 , 35 , 39 , 49 , 51 , 58 ], which actually leads to the development of fatigue syndrome. Several studies have demonstrated an association between chronic fatigue syndrome and orthostatic intolerance, predominantly postural orthostatic tachycardia syndrome [ 7 , 59 , 60 ].…”
Section: Changes In the Cardiovascular System During Postnatal Ontogenesis As An Anthropogenic Basis For The Physiology And Pathology Of mentioning
confidence: 99%
“…The proposed “anthropogenic model” (periodization) of adaptation to the Earth’s gravity in the process of formation in the womb and during human life in specific conditions of bipedalism [ 6 , 11 , 12 , 32 ] is projected into all three stages of postnatal human development (pre-definitive, definitive, and post-definitive) and are well-synchronized with the accepted periodization of human physical development.…”
Section: Changes In the Cardiovascular System During Postnatal Ontogenesis As An Anthropogenic Basis For The Physiology And Pathology Of mentioning
Applying human biological evolution to solve topical problems of medicine and preventive cardiology was inspired by the realization of the need for clinical and experimental studies of biological (evolutionary) prerequisites in the occurrence of a pathology. Although it has been stated that there is a need to provide a full biological understanding of features, including those that increase an animal’s vulnerability to diseases, unfortunately, in this regard, erectile and associated adaptations to the Earth’s gravity in their physiological and pathological manifestations have not been considered. At the same time, it should be noted that humans, unlike other animal species, have the greatest vulnerability of the cardiovascular system (CVS). The latter is associated with fundamental differences in the functioning and regulation of the CVS by the influence of gravity on blood circulation in humans as upright creatures. Based on a review of comparative physiological, ontogenetic, and clinical studies from an evolutionary perspective, the idea of adaptation to the Earth’s gravity when walking upright in humans is justified as an anthropogenic basis for the physiology and pathology of the cardiovascular system and hemodynamic support systems (physio-anthropology and pathological anthropology).
“…The reality of the significant influence of gravity (the hydrostatic effect) on hemodynamics in humans, as an upright creature, has already been demonstrated [ 6 , 9 , 26 , 33 , 37 , 38 ] (Fig. 2 ).…”
Section: Physiological Antropology Of Cardiovascular Adaptation To the Earth’s Gravitymentioning
confidence: 99%
“…Figure 5 clearly presents that the share of hyperkinetic (type III) hemodynamic reaction to the change of the influence of gravity clearly increases during the reproductive age and, especially, during the post-reproductive age. At the same time, this transition is enhanced by comorbid conditions, especially by the presence of arterial hypertension in both humans and monkeys, as representatives of the same order of primates [ 6 , 11 , 20 , 21 , 23 , 27 , 28 , 39 – 42 ]. Fig.…”
Section: Physiological Antropology Of Cardiovascular Adaptation To the Earth’s Gravitymentioning
confidence: 99%
“…Therefore, the “anthropogenic model” is considered not only as a step-by-step ontogenetic formation of upright walking, which is the main postural and motor form of human activity as an upright being, but also as a permanent organizational adaptation to Earth’s gravity in all of its physiological and pathological manifestations [ 3 , 4 , 6 , 8 , 29 , 37 , 49 , 52 – 54 ].…”
Section: Changes In the Cardiovascular System During Postnatal Ontogenesis As An Anthropogenic Basis For The Physiology And Pathology Of mentioning
confidence: 99%
“…This is due to a violation of the daily rhythm with an increase in the time spent in a vertical position with a shortening of the lying period, including violations of the natural synchronization of the “day-night” biorhythm. The abovementioned factors result in an increase in the body’s tension in the anti-gravity mode [ 1 – 4 , 6 , 29 , 32 , 35 , 39 , 49 , 51 , 58 ], which actually leads to the development of fatigue syndrome. Several studies have demonstrated an association between chronic fatigue syndrome and orthostatic intolerance, predominantly postural orthostatic tachycardia syndrome [ 7 , 59 , 60 ].…”
Section: Changes In the Cardiovascular System During Postnatal Ontogenesis As An Anthropogenic Basis For The Physiology And Pathology Of mentioning
confidence: 99%
“…The proposed “anthropogenic model” (periodization) of adaptation to the Earth’s gravity in the process of formation in the womb and during human life in specific conditions of bipedalism [ 6 , 11 , 12 , 32 ] is projected into all three stages of postnatal human development (pre-definitive, definitive, and post-definitive) and are well-synchronized with the accepted periodization of human physical development.…”
Section: Changes In the Cardiovascular System During Postnatal Ontogenesis As An Anthropogenic Basis For The Physiology And Pathology Of mentioning
Applying human biological evolution to solve topical problems of medicine and preventive cardiology was inspired by the realization of the need for clinical and experimental studies of biological (evolutionary) prerequisites in the occurrence of a pathology. Although it has been stated that there is a need to provide a full biological understanding of features, including those that increase an animal’s vulnerability to diseases, unfortunately, in this regard, erectile and associated adaptations to the Earth’s gravity in their physiological and pathological manifestations have not been considered. At the same time, it should be noted that humans, unlike other animal species, have the greatest vulnerability of the cardiovascular system (CVS). The latter is associated with fundamental differences in the functioning and regulation of the CVS by the influence of gravity on blood circulation in humans as upright creatures. Based on a review of comparative physiological, ontogenetic, and clinical studies from an evolutionary perspective, the idea of adaptation to the Earth’s gravity when walking upright in humans is justified as an anthropogenic basis for the physiology and pathology of the cardiovascular system and hemodynamic support systems (physio-anthropology and pathological anthropology).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
