Consequences of infection pressure and protein nutrition on periparturient resistance to Teladorsagia circumcincta and performance in ewes

Kidane, Alemayehu; Houdijk, J.G.M.; Tolkamp, B.J.; Athanasiadou, Spiridoula; Kyriazakis, Ι.

doi:10.1016/j.vetpar.2009.06.039

Cited by 22 publications

(10 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results could potentially be attributed to two mechanisms: a cost of reproduction, in the form of fewer resources remaining for allocation to immune‐mediated parasite resistance (Sheldon & Verhulst, ), or an increase in exposure across the season as hungry females spend more time foraging in nutrient‐rich, but also parasite‐rich tussock vegetation (Hutchings, Milner, Gordon, Kyriazakis, & Jackson, ). While changes in exposure could explain some of the change in FEC across the season, experimental studies in domestic sheep show that variation in exposure has a weaker effect on the PPR compared to variation in nutrition (Kidane, Houdijk, Tolkamp, Athanasiadou, & Kyriazakis, ). Our results add to the evidence from wild populations that females making a large reproductive effort experience a cost in the form of increased parasite burden (Knowles et al, ; Nordling et al, ; Richner et al, ).…”

Section: Discussionmentioning

confidence: 99%

“…While changes in exposure could explain some of the change in FEC across the season, experimental studies in domestic sheep show that variation in exposure has a weaker effect on the PPR compared to variation in nutrition (Kidane, Houdijk, Tolkamp, Athanasiadou, & Kyriazakis, 2009). Our results add to the evidence from wild populations that females making a large reproductive effort experience a cost in the form of increased parasite burden (Knowles et al, 2009;Nordling et al, 1998;Richner et al, 1995).…”

Section: We Examined Between-individual Variation In Fec Within a 4-mentioning

confidence: 99%

See 1 more Smart Citation

Reproductive effort influences intra‐seasonal variation in parasite‐specific antibody responses in wild Soay sheep

Hayward

Pilkington²,

Wilson

et al. 2019

Functional Ecology

View full text Add to dashboard Cite

A trade‐off between reproduction and immune function has been suggested to potentially underpin between‐individual and genetic variation in reproductive strategy, immunity and life span, with potential consequences for host and parasite dynamics. Previous studies in wild animal populations have shown that experimentally induced or natural variation in reproductive effort is negatively associated with general immune markers. Few studies, however, have tackled this question by measuring specific immune responses against prevalent pathogens, and only rarely has variation in immune measures been linked to parasite burden, making it impossible to draw conclusions about the functional relevance of covariation between reproductive effort and immune markers. We collected faecal samples in a longitudinal manner from wild female Soay sheep across late pregnancy and early lactation and measured gastrointestinal nematode faecal egg count (FEC) and worm‐specific antibody responses. Faecal egg count was highly repeatable, with c. 80% of variation due to between‐individual differences, while three isotypes of worm‐specific and total antibodies had moderate repeatability (range: 11%–43%). Females making a greater reproductive effort (those that reproduced, and especially those with heavier litters) showed a more rapid increase in FEC across the season, while non‐reproducing females and those producing lighter litters experienced lower FEC and had higher antibody levels. Associations between antibodies and FEC were complex: worm‐specific immunoglobulin (Ig) G was negatively associated with FEC, while total IgM was positively associated, emphasizing the importance of measuring both immune markers and parasite burden in ecological studies. Our results support the predicted trade‐off between reproductive effort and parasite‐specific immunity: high reproductive effort can limit the ability of individuals to defend themselves against prevalent parasites, with potential downstream consequences for fitness and parasite transmission. A plain language summary is available for this article.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: We Examined Between-individual Variation In Fec Within a 4-mentioning

confidence: 99%

Reproductive effort influences intra‐seasonal variation in parasite‐specific antibody responses in wild Soay sheep

Hayward

Pilkington²,

Wilson

et al. 2019

Functional Ecology

View full text Add to dashboard Cite

show abstract

“…Diversos trabalhos têm mostrado redução do OPG com a suplementação proteica no periparto (29,(32)(33)(34)(35)(36) . Ovelhas natural ou experimentalmente infectadas e suplementadas com níveis de proteína abaixo do requerimento no final da gestação e inicio da lactação mostraram aumento do OPG no periparto maior que ovelhas suplementadas com níveis acima do requerimento (37)(38) .…”

Section: Resultsunclassified

Resistência À Verminose E Suplementação Proteica No Periparto: Efeito No Parasitismo E No Desempenho Reprodutivo De Ovelhas Do Grupamento Racial Pantaneiro

et al. 2017

View full text Add to dashboard Cite

ResumoOs objetivos do trabalho foram avaliar o efeito do grau de resistência à verminose e da suplementação proteica nos índices reprodutivos e no parasitismo em ovelhas do grupamento racial Pantaneiro. As ovelhas foram classificadas pelo número de ovos de nematodas por grama de fezes (OPG) como resistentes (RR), sensíveis (SS) e intermediárias (RS), e submetidas (SUPL) ou não (NSUPL) à suplementação durante o terço final da gestação e na lactação. Em dois ciclos reprodutivos, a cada 28 dias, as ovelhas foram pesadas e tratadas com anti-helmínticos quando o OPG apresentava-se ≥ 4000. O peso das ovelhas não foi influenciado pelo grau de resistência aos nematódeos e a suplementação teve efeito no peso somente no período em que foi ofertada. As taxas de natalidade e de desmame não foram influenciadas pelo grau de resistência e pela suplementação. A taxa de mortalidade de crias foi menor no grupo SUPL. A taxa de mortalidade de ovelhas foi três vezes mais elevada no grupo SS em relação ao grupo RR e o peso das crias foi menor no grupo SS em relação aos grupos RR e RS. Os três grupos mostraram picos no OPG durante o terço final da gestação, mas as médias foram sempre menores no grupo RR que, no geral, necessitaram 2,5 vezes menos tratamentos anti-helmínticos que as SS. A suplementação não apresentou correlação com o OPG e com o número de tratamentos anti-helmínticos. A classificação de ovelhas pelo OPG em resistentes aos nematodas proporcionou menor número de tratamentos antihelmínticos, menor taxa de mortalidade de ovelhas e peso maior das crias ao nascimento.

show abstract

“…This effect is due to an increase in gastrointestinal protein turnover, a nutritional cost for increased immune stimulation by the parasites, direct gastrointestinal blood loss, and possibly a reduced feed intake. [14][15][16] The quality of the diet appears to be more significant than the quantity. Increasing dietary metabolizable protein intake in the face of subclinical parasitism will help meet production goals.…”

Section: Gastrointestinal Parasitesmentioning

confidence: 99%

“…[14][15][16] The quality of the diet appears to be more significant than the quantity. 16,19,20 In animals with access to forage containing plants with condensed tannins, expected benefits include reduced gastrointestinal parasite burden, altered parasite life cycle, reduced parasite larval numbers, and stimulation of the host's immune system. 15 Rumen-protected methionine also has a positive effect on wool production and weight gain in T. colubriformis-infected lambs.…”

Section: Gastrointestinal Parasitesmentioning

confidence: 99%

Feeding and Nutrition

Rankins¹,

Pugh²

2012

Sheep and Goat Medicine

View full text Add to dashboard Cite

Consequences of infection pressure and protein nutrition on periparturient resistance to Teladorsagia circumcincta and performance in ewes

Cited by 22 publications

References 43 publications

Reproductive effort influences intra‐seasonal variation in parasite‐specific antibody responses in wild Soay sheep

Reproductive effort influences intra‐seasonal variation in parasite‐specific antibody responses in wild Soay sheep

Resistência À Verminose E Suplementação Proteica No Periparto: Efeito No Parasitismo E No Desempenho Reprodutivo De Ovelhas Do Grupamento Racial Pantaneiro

Feeding and Nutrition

Contact Info

Product

Resources

About