Consequence of the antioxidant activities and tyrosinase inhibitory effects of various extracts from the fruiting bodies of Pleurotus ferulae

Abstract

This study was initiated to screen the antioxidant activities, tyrosinase inhibitory effects on the fruiting bodies of Pleurotus ferulae extracted with acetone, methanol and hot water. The antioxidant activities were performed on β-carotene-linoleic acid, reducing power, DPPH, ferrous ions chelating abilities, and xanthine oxidase. In addition to this, phenolic compounds were also analyzed. The methanolic extract showed the strongest β-carotene-linoleic acid inhibition and high reducing power as compared to other extracts. The scavenging effects on DPPH radicals, the acetonic and methanolic extracts were more effective than hot water extracts. The strongest chelating effect was obtained from the methanolic extract as compared to the tested synthetic antioxidant. Gallic acid, protocatechuic acid, caffeic acid, vanillin, ferulic acid, naringin, resveratrol, naringenin, hesperetin, formononetin and biochanin-A were detected from acetonitrile and hydrochloric acid (5:1) solvent extract. Xanthine oxidase and tyrosinase inhibitory activities of acetonic, methanolic, and hot water extracts of P. ferulae increased with increasing concentration. The results suggested that consumption of P. ferulae might be beneficial to the antioxidant, xanthine oxidase, and tyrosinase protection system of the human body against oxidative damage and others complications.

Mushrooms extracts and compounds in cosmetics, cosmeceuticals and nutricosmetics—A review

“…P.Kumm. (Alam et al, 2010;Hapsari et al, 2012) and Pleurotus salmoneostramineus Vassil . Although Pleurotus species are the most studied mushroom species with reported anti-tyrosinase potential, none of those studies were able to identify the bioactive metabolites responsible for this activity.…”

“…Other Pleurotus species with reported anti-tyrosinase activity are Pleurotus ferulae Quél. (Alam et al, 2012); Pleurotus nebrodensis (Inzenga) Quél. ; Pleurotus ostreatus (Jacq.…”

Pleurotus ferulae water extract enhances the maturation and function of murine bone marrow-derived dendritic cells through TLR4 signaling pathway

“…Pleurotus ferulae (PF) is an edible mushroom with high nutritional value and significant pharmacological properties, which grows on the living rhizome trunks of Ferula asafoetida in the Gobi desert and is mainly distributed in Xinjiang, China. PF produces various biologically functional components and exerts anti-oxidant, antitumor, and anti-microbial activities [18][19][20]. Recently, our study showed that PF ethanol extract (PFEC) suppressed tumor growth through induction of cell apoptosis, and inhibition of cell proliferation and migration [21].…”

Consumption of vitamin D2 enhanced mushrooms is associated with improved bone health

“…Higher Tb.BMD, BV/TV and Tb.Th and lower BS/BV in NPM mice compared with OVX mice are also in agreement with another study in which nonirradiated Pleurotus mushroom extracts were shown to alleviate the decrease in Tb.BMD in osteoporotic mice [36]. P. ferulae contains various phenolic and flavonoid compounds [37], as well as phytochemicals that have been shown to elicit a bone-protective effect [31,38,39].…”