Consensus Conference on Breast Conservation

Schwartz, Gordon F.; Veronesi, Umberto; Clough, Krishna B.; Dixon, JM; Fentiman, Ian S.; Heywang‐Köbrunner, Sylvia H.; Holland, Roland; Hughes, Kevin S.; Mansel, Robert E.; Margolese, Richard G.; Mendelson, Ellen B.; Olivotto, Ivo A.; Palazzo, Juan; Solin, Lawrence J.

doi:10.1016/j.jamcollsurg.2006.04.009

Cited by 81 publications

(38 citation statements)

References 7 publications

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“…In the present study, we also found that tumor size, as estimated by preoperative palpation, affected the indications for IFSE, in that IFSE was used more frequently for SLNB and BS in patients with tumors ≤20 mm. This finding may demonstrate that preoperative estimation of tumor size is a key factor in determining whether BS will be performed [46,47], as BS is safest when tumors are small [48]. Conversely, patients with large tumors have a higher probability of having axillary lymph node metastasis [49,50] and a greater risk of complications from a SLNB [51,52].…”

Section: Discussionmentioning

confidence: 99%

Application of intraoperative frozen section examination in the management of female breast cancer in China: a nationwide, multicenter 10-year epidemiological study

et al. 2014

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BackgroundIntraoperative frozen section examination (IFSE) during breast cancer surgery can partly reflect the status of surgical treatment since the surgical method used directly determines the purpose of IFSE use in disease management. This study aims to investigate the application of, changing trends in, and factors influencing IFSE in the management of female breast cancer in China.MethodsWe collected the sociodemographic and clinical data of 4,211 breast cancer patients between 1999 and 2008 and statistically analyzed these data using χ2 or Fisher’s exact tests.ResultsA total of 2,283 (54.22%) patients with breast cancer underwent IFSE. During the 10-year study period, IFSE use was associated with an increase in the number of sentinel lymph node biopsies (SLNB) and breast-conserving surgeries (BS) performed, with significant regional differences noted in this trend (P <0.05). Patients’ education, occupation, age, tumor size estimated by preoperative palpation, and the use of imaging examinations affected the purpose of IFSE use (P <0.05).ConclusionsOur results show that the purpose of IFSE in the surgical treatment of breast cancer in China is gradually approaching that in developed countries. We believe that policymakers must address the differences in breast cancer treatment based on the socioeconomic status of patients. Lastly, the use of IFSE for determining tumor characteristics should be avoided as far as possible, and patient education and breast cancer screening programs tailored to the Chinese population should be established. Our findings may guide the formulation of breast cancer control strategies in China and other low-income countries.

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Section: Discussionmentioning

confidence: 99%

Application of intraoperative frozen section examination in the management of female breast cancer in China: a nationwide, multicenter 10-year epidemiological study

et al. 2014

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“…Conservation has allowed improved cosmetic results with no significant difference in overall survival compared to traditional mastectomy [1,2]. Recently an increasing number of patients with more advanced breast tumors, previously not eligible for breast conservation surgery, have been treated with neoadjuvant chemotherapy.…”

Section: Introductionmentioning

confidence: 99%

Does MRI predict pathologic tumor response in women with breast cancer undergoing preoperative chemotherapy?

Segara

Krop

Garber

et al. 2007

Journal of Surgical Oncology

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“…These lesions are defined as asymmetric densities, deep seated lesions, and calcifications (10). Current published literature suggests breast-conserving therapy, including lumpectomy or wide-to-local excision together with adjuvant radiotherapy to the tumor bed in patients with nonpalpable lesions (11). Breast-conserving surgery is considered the reference standard treatment for early BCa (12).…”

Section: Introductionmentioning

confidence: 99%

Impact of Breast Tomosynthesis for Evaluating Specimen of Breast Carcinoma: Initial Results

Akin¹,

Balci²,

Gezer³

et al. 2018

Cyprus J Med Sci

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BACKGROUND/AIMSTo evaluate the impact of digital breast tomosynthesis (DBT) for assessing specimens of breast carcinoma (BCa) in terms of comparing with other diagnostic tools. MATERIALS and METHODSBetween November 2014 and May 2015, patients who underwent wire-guided breast biopsy with mammography (MG), specimen radiography (RG), and digital specimen tomosynthesis (DST) examinations were evaluated. Two breast radiologists retrospectively assessed the results in consensus. Breast lesions were classified according to the Breast Imaging Reporting and Data Systems (BI-RADS). In mass described cases, the longest axes of the masses were measured; and in calcification described cases, the longest axes of the calcifications were measured. All findings were compared with macroscopic measurements. Statistical analyses were performed; p<0.05 was considered significant. RESULTSIn total, 85 specimens were evaluated. The mean age was 54.2±10.8 years. Of the 85 specimens, 46 lesions were malignant and 39 lesions were benign. The average mass sizes were 14±9.7 and 13±6.8 mm in diagnostic MG and DBT, respectively. In specimen RG and DST, the average mass sizes were 12±6 mm and 12±6.2 mm, respectively. The mean macroscopic mass size was 12±6.3 mm. There was a statistical significant difference between diagnostic MG and specimen RG-DST findings regarding mass sizes (p=0.02 and p=0.01, respectively). BI-RADS evaluations of specimen RG and diagnostic and specimen TS were similar but different from those of diagnostic MG (p<0.001). CONCLUSIONThe exact detection of BCa specimen and its BI-RADS features can be diagnosed using DST; lesion size, with specimen and diagnostic DBT. Additionally, DBT can help diagnose preoperative structural distortion or asymmetric densities.

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Consensus Conference on Breast Conservation

Cited by 81 publications

References 7 publications

Application of intraoperative frozen section examination in the management of female breast cancer in China: a nationwide, multicenter 10-year epidemiological study

Application of intraoperative frozen section examination in the management of female breast cancer in China: a nationwide, multicenter 10-year epidemiological study

Does MRI predict pathologic tumor response in women with breast cancer undergoing preoperative chemotherapy?

Impact of Breast Tomosynthesis for Evaluating Specimen of Breast Carcinoma: Initial Results

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