Consciousness Recovery in Traumatic Brain Injury: A Systematic Review Comparing Modafinil and Amantadine
Ali Seifi,
Sina Hassannezhad,
Reza Mosaddeghi-Heris
et al.
Abstract:Objectives
Acute traumatic brain injury is one of the most common causes of death and disability. Reduction in the level of consciousness is a significant complication that can impact morbidity. Glasgow Coma Scale (GCS) is the most widely used method of assessing the level of consciousness. Neurostimulants such as amantadine and modafinil are common pharmacologic agents that increase GCS in patients with brain trauma. This study aimed to compare the effectiveness of these 2 drugs.
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