Connotation and scientific research points of processing of Mongolian medicinal materials

Song, Lin; Sa, Chula; Li, Mei; Du, Lina; Wu, Sarula; Su, Rigugaqiqige; Dao, Ligema

doi:10.1016/j.chmed.2022.06.002

Cited by 3 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Introductionmentioning

confidence: 99%

“…Based on the special geographical location, unique living habits and profound historical origin of the birthplace of Mongolian medicine, it has potential advantages in the treatment of liver diseases. [4][5][6] The Mongolian plateau has a high terrain and monotonous food, with limited vegetables and fruits. [7] The local residents have a habit of consuming sugary drinks and milk, and meat occupies a dominant position in their diet.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Quantitative comparison on the similarities and differences of Mongolian medicines in the treatment of liver diseases between China and Mongolia based on data mining

Huang,

Zhou,

Chen

et al. 2023

Sci Tradit Chin Med

View full text Add to dashboard Cite

Objective The R language was used to quantitatively compare the medication patterns of Mongolian medicines used for the treatment of liver diseases between China and Mongolia, with a view to provide a reference for the research and clinical application of Mongolian medicines in the treatment of liver diseases. Methods The Mongolian medicinal prescriptions used for treating liver disease in Mongolia were collected from the Mongolian Pharmacy and Mongolian Treatment Guide for Common diseases in Mongolian Medicine, and those used in China were collected from the Inner Mongolia Standard for Mongolian Proprietary Medicine and Annotation of Mongolian Medicine Preparation Specifications. After the database was established, the frequency, properties, and tastes of the Mongolian medicines were analyzed, and R studio was used for the association rules analysis and cluster analysis. Results A total of 27 prescriptions used in Inner Mongolia, China, were collected involving 105 Mongolian medicines, with a total frequency of 284. Among them, there were 18 high-frequency medicines (frequency ≥5), which had a frequency of 147, accounting for 51.76% of the total frequency. The medicine with the highest frequency (14, 4.93%) was Carthamus tinctorius L.. The analysis of the medicine data in China revealed 15 association rules. A total of 21 prescriptions used in Mongolia were collected, involving 92 Mongolian medicines, with a total frequency of 254. Among them, there were 17 high-frequency (frequency ≥5) medicines, with a total frequency of 124 (48.82%). The medicine with the highest frequency (13, 5.12%) was Carthamus tinctorius L.. The analysis of the medicine data in Mongolia revealed 79 association rules. In both regions, the high-frequency medicines used for treating liver disease commonly had cool or warm property with bitter or sweet taste. Conclusions Carthamus tinctorius L., Terminalia chebula Retz., and other Mongolian medicines are commonly used to treat liver diseases in Inner Mongolia and Mongolia. The Mongolian medicines with cool or warm property and bitter, sweet, or astringent taste are commonly used to protect the liver.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quantitative comparison on the similarities and differences of Mongolian medicines in the treatment of liver diseases between China and Mongolia based on data mining

Huang,

Zhou,

Chen

et al. 2023

Sci Tradit Chin Med

View full text Add to dashboard Cite

show abstract

Cymbaria daurica L.: A Mongolian herbal medicine for treating eczema via natural killer cell-mediated cytotoxicity pathway

Huang

Guo

et al. 2023

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Screening for anti-influenza virus compounds from traditional Mongolian medicine by GFP-based reporter virus

Nie,

Li,

Zhang

et al. 2024

Front. Cell. Infect. Microbiol.

View full text Add to dashboard Cite

IntroductionScreening for effective antiviral compounds from traditional Mongolian medicine not only aids in the research of antiviral mechanisms of traditional medicines, but is also of significant importance for the development of new antiviral drugs targeting influenza A virus. Our study aimed to establish high-throughput, rapid screening methods for antiviral compounds against influenza A virus from abundant resources of Mongolian medicine.MethodsThe use of GFP-based reporter viruses plays a pivotal role in antiviral drugs screening by enabling rapid and precise identification of compounds that inhibit viral replication. Herein, a GFP-based reporter influenza A virus was used to identify potent anti-influenza compounds within traditional Mongolian medicine.ResultsOur study led to the discovery of three active compounds: Cardamonin, Curcumin, and Kaempferide, all of which exhibited significant antiviral properties in vitro. Subsequent analysis confirmed that their effectiveness was largely due to the stimulation of the antiviral signaling pathways of host cells, rather than direct interference with the viral components, such as the viral polymerase.DiscussionThis study showcased the use of GFP-based reporter viruses in high-throughput screening to unearth antiviral agents from traditional Mongolian medicine, which contains rich antiviral compounds and deserves further exploration. Despite certain limitations, fluorescent reporter viruses present substantial potential for antiviral drug screening research due to their high throughput and efficiency.

show abstract

Connotation and scientific research points of processing of Mongolian medicinal materials

Cited by 3 publications

References 2 publications

Quantitative comparison on the similarities and differences of Mongolian medicines in the treatment of liver diseases between China and Mongolia based on data mining

Quantitative comparison on the similarities and differences of Mongolian medicines in the treatment of liver diseases between China and Mongolia based on data mining

Cymbaria daurica L.: A Mongolian herbal medicine for treating eczema via natural killer cell-mediated cytotoxicity pathway

Screening for anti-influenza virus compounds from traditional Mongolian medicine by GFP-based reporter virus

Contact Info

Product

Resources

About