“…The progress of neuroimaging techniques, in particular diffusion magnetic resonance imaging (dMRI) and functional MRI, as well as post-processing (tractography) and network analysis methods, has enabled the in vivo study of the structural and functional connectivity that form the brain connectome. Connectomics has so far confirmed the impairment of network connectivity in AD observed by neuroanatomical and neuropathological studies, supporting the role of white matter degeneration in the disease, and the fact that part of the symptoms are due to disconnection of distant cortical regions (Daianu et al, 2013b(Daianu et al, , 2013aFischer et al, 2015;Mallio et al, 2015;Nir et al, 2012Nir et al, , 2015Prescott et al, 2014).…”