A
q
-rung orthopair fuzzy set (q-ROFS) is a robust approach for fuzzy modeling, computational intelligence, and multicriteria decision-making (MCDM) problems. The aim of this paper is to study the topological structure on q-ROFSs and define the idea of
q
-rung orthopair fuzzy topology (q-ROF topology). The characterization of q-ROF
α
-continuous mappings between q-ROF topological spaces and q-ROF connectedness is investigated. Some relationships of different types of
q
-rung orthopair fuzzy connectedness are also investigated. Additionally, the “
q
-rung orthopair fuzzy weighted product model” (q-ROF WPM) is developed for MCDM of a hierarchical healthcare system. Due to limited and insufficient resources, a hierarchical healthcare system (HHS) is very effective to deal with the increasing problems of healthcare. Recognizing the stage of a disease with the symptoms, ranking the critical condition of patients, and referring patients to feasible hospitals are key features of HHS. A HHS will provide healthcare services in three levels, a primary health centers for initial stage of disease, secondary hospitals for secondary stage of disease, and tertiary hospital for the third-order stage. A numerical example is illustrated to demonstrate the efficiency of q-ROF WPM and advantages of HHS.