Conjunctival tumors in children

Shields, Carol L.; Shields, Jerry A.

doi:10.1097/icu.0b013e32823ecfbb

Cited by 84 publications

(104 citation statements)

References 48 publications

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“…Our study shows that the histopathological diagnoses of patients from a referral hospital, which may have resulted in biased data, because tumor incidences may differ from those seen in clinical practice in the general population. In this series, melanocytic lesions were the most common (30.91%), which is consistent with other reported series of patients in both children (23-83%) (3)(4)(5)(6) and adults (53%) (7) Conjunctival nevi are the most common melanocytic tumors and are usually occur before 20 years of age. The intensity of the pigment increases in 5% of these tumors, 7% grow in size with increasing age, and less than 1% become malignant.…”

Section: Discussionsupporting

confidence: 80%

“…The intensity of the pigment increases in 5% of these tumors, 7% grow in size with increasing age, and less than 1% become malignant. (6) . Management is usually expectant (measurement of the lesion and taking photographs for future comparisons), and if major changes are documented, surgical removal of the lesion must be considered (2,6) .…”

Section: Discussionmentioning

confidence: 99%

“…(6) . Management is usually expectant (measurement of the lesion and taking photographs for future comparisons), and if major changes are documented, surgical removal of the lesion must be considered (2,6) . Choristomatous lesions were the second most common.…”

Section: Discussionmentioning

confidence: 99%

“…described the clinicopathological characteristics of 42 conjunctival tumors that were surgically removed from children; 83% of the cases in this series were pigmented conjunctival nevi (5) . Further, in a clinical series of 262 pediatric patients, Shields et al reported melanocytic tumors in 67% of the cases (6) . The aim of this paper is to report the frequency and histopathologic diagnosis of conjunctival tumors that were surgically removed from children under 14 years of age from 1988 to 2013 at an eye care center from a developing country.…”

Section: Introductionmentioning

confidence: 99%

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Conjunctival tumors in children: histopathologic diagnosis in 165 cases

Zimmermann-Paiz¹,

Riva²

2015

Arquivos Brasileiros De Oftalmologia

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(3-6).Cunha et al. reported the histopathology of 282 consecutive, clinically diagnosed epibulbar tumors excised from children. The most common tumors were melanocytic (23%), choristomatous (22%), and benign epithelial (10%) tumors (3) . In another case series, Elsas et al. reported 302 cases of epibulbar tumors in children, comprising 33% choristomas, 29% conjunctival nevi, 11% epithelial inclusion cysts, 7% papillomas, 6% pyogenic granulomas, and 5% granulomas (4) . Beby et ABSTRACT Purpose: Conjunctival tissue tumors have a varied presentation, and few series studies on pediatric patients have been published. The objective of this paper is to report the histopathologic diagnoses (spanning over 1988-2013) of conjunctival tumors in children younger than 14 years. Methods: We conducted a retrospective, descriptive, and observational study by reviewing the database of all children in whom a conjunctival tumor was surgically removed at Hospital de Ojos y Oídos "Dr. Rodolfo Robles V., " Benemérito Comité Pro Ciegos y Sordos de Guatemala. The data pertaining to gender, age, and histopathologic diagnosis of all cases was collected. The same ocular pathologist made all diagnoses. Results: One hundred sixty-five cases were found, with a mean age of 7.88 years, being 91 (55.15%) male subjects. Melanocytic lesions were the most common tumors found (30.91% of cases), with only one case (0.60%) being malignant. Conclusions: Melanocytic lesions were the most common tumors found, and of all the cases, only one was malignant; this was in a patient with xeroderma pigmentosum. These findings are consistent with those reported in other studies regarding the frequencies of the histopathology of conjunctival tumors in the pediatric population.

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Conjunctival tumors in children: histopathologic diagnosis in 165 cases

Zimmermann-Paiz¹,

Riva²

2015

Arquivos Brasileiros De Oftalmologia

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“…13 In a quarter of cases, the pathological diagnoses were different from the clinical diagnosis, making it legitimate to recommend a systematic pathological analysis.…”

Section: Discussionmentioning

confidence: 99%

Characterization of all Surgical Specimens Provided by a Portuguese Department of Ophthalmology over a 13 Year Period

2017

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Introduction: We intend to evaluate clinically, topographically and morphologically all surgical specimens sent by the Department of Ophthalmology of Hospital de Braga to the Department of Pathology of the same hospital.Material and Methods: Two hundred and fifty eight surgically obtained specimens, from the Department of Ophthalmology of Hospital de Braga, analyzed in the Department of Pathology, from January 2002 to June 2015, were characterized. Data was arranged according to year, age, sex, topography and morphological diagnosis according to the SNOMED® coding system.Results: Mean age at time of diagnosis was 54.6 years old; 52.3% were male subjects. The number of specimens was relatively stable until the year 2010, with a significant increase between 2011 and 2013. Most specimens sent corresponded to eyelid (54.7%), followed by conjunctiva (26.7%); the most common pathological diagnosis was malignant epithelial lesions (22.48%), followed by melanocytic tumours (22.09%) and benign epithelial lesions (17.05%).Discussion: The results are distinct from previous publications presumably because of differences between the populations submitted to analysis.Conclusion: This is the first indexed publication characterizing surgical specimens from a Department of Ophthalmology in Portugal; moreover, it also includes an extensive review of global epidemiological data about ophthalmic surgical specimens.

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Conjunctival Papilloma

Kaliki¹,

Arepalli²,

Shields³

et al. 2013

JAMA Ophthalmol

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Conjunctival papilloma is a benign epithelial tumor occurring in both children and adults with varying clinical features and outcomes. In this article, we describe our experience regarding the difference in the clinical features and outcomes of conjunctival papilloma based on age at initial examination.Objective: To evaluate the clinical features, treatment, and outcomes in patients with conjunctival papilloma based on age at initial examination.

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Conjunctival tumors in children

Abstract: Conjunctival nevus is the most common conjunctival tumor in children and fewer than 1% evolve into melanoma over time.

Cited by 84 publications

References 48 publications

Conjunctival tumors in children: histopathologic diagnosis in 165 cases

Conjunctival tumors in children: histopathologic diagnosis in 165 cases

Characterization of all Surgical Specimens Provided by a Portuguese Department of Ophthalmology over a 13 Year Period

Conjunctival Papilloma

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