Conjunctival Stromal Tumors

Pe’er, Jacob; Frenkel, Shahar

doi:10.1007/978-3-030-06046-6_18

Cited by 1 publication

(1 citation statement)

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“…Risk factors include exposure to ultraviolet light B (2,3) ; therefore, a higher incidence is observed in countries close to the equator (4) . Other risk factors associated with OSSN are fair skin, human papilloma virus infection (5,6) , human immunodeficiency virus (7) , other forms of immunosuppression (8)(9)(10)(11)(12)(13) , age, male sex (1,2,14) , and xeroderma pigmentosum (2,15) .…”

Section: Introductionmentioning

confidence: 99%

Nova abordagem de baixo custo para neoplasia escamosa da superficie ocular usando fotocoagulação tipo pattern scanning

Rodriguez¹,

Sancho²,

Kange³

et al. 2020

Arquivos Brasileiros De Oftalmologia

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To evaluate the safety and 12-month effect of treatment with pattern scanning laser photocoagulation for ocular surface squamous neoplasia in a low-resource setting with extremely limited access to an operating room. Methods: Adult patients with a clinical diagnosis of ocular surface squamous neoplasia underwent a complete ophthalmologic examination. After topical anesthesia and instillation of toluidine blue 1%, the lesion was treated using pattern scanning photocoagulation for a duration time that varied from 20 to 100 ms and power from 600 to 1,800 mW. Patients were examined on a weekly basis for the first month and underwent weekly retreatment of the remaining lesions, as necessary. Patients had a minimum follow-up of 12 months. Results: Thirty-eight patients (38 eyes) were included. All patients had clinical ocular surface squamous neoplasia that was confirmed by impression cytology. The age of patients ranged from 40 to 83 years (average: 65.5 years) and 28 of them were males (74%). The patients were divided into two groups: group I (immunocompetent) and group II (immunosuppressed). In group I, 23 patients (74%) presented complete response with lesion control after laser treatment alone. In group II, two of seven patients (28%) showed treatment response during the follow-up. The average number of treatments was 2.5 (one to six laser treatments). Procedures were well tolerated. Conclusion: Short-term results of the laser photocoagulation approach for the treatment of ocular surface squamous neoplasia conjunctival lesions were favorable, with a 74% success rate observed in immunocompetent patients. This novel strategy is a less resource-intensive alternative that could demonstrate its usefulness in settings with shortages in operating rooms and in recurrent cases. Studies with longer follow-ups and larger sample sizes are warranted to confirm our findings and evaluate the effectiveness of laser treatment in association with topical chemotherapy.

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