“…Dry eye (DE) disease is the most frequent manifestation of ocular GVHD, and is reported to occur, to a various degree, in 40-76% of patients [1,2]. Clinical features consist of conjunctival fibrosis, punctate and/or filamentous keratopathy, chronic blepharitis, atrophy and irregularity of the eyelid margin, which may eventually induce keratinization of the tarsal conjunctiva and symblepharon [3]. Symptoms include irritation, burning, foreign body sensation, pain, photophobia and blurred vision, with deeply impaired quality of life and daily activities [4].…”