Conjugated Polymers for Near‐Infrared Photothermal Therapy of Cancer

Facile Incorporation of “Aggregation-Induced Emission”-Active Conjugated Polymer into Mesoporous Silica Hollow Nanospheres: Synthesis, Characterization, Photophysical Studies, and Application in Bioimaging

“…In the last decade, conjugated polymers (CPs) with an alternating array of donor (D) and acceptor (A) in the polymer backbone have attracted their applications in bioimaging, , biosensing, photodynamic therapy, light-emitting diodes, , solar cells, thin-film transistors, , and explosive sensors. − The highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) energy levels could be easily controlled by choosing the appropriate electron-rich (donor) and electron-deficient (acceptor) moieties in the polymer backbone to tune the absorption and emission wavelengths. , The introduction of propeller-shaped AIEgens such as tetraphenylethylene (TPE) and triphenylamine (TPA) in the CP backbone is to avoid the aggregation caused quenching (ACQ) problem in aggregated or in solid state. , For the successful utilization of “aggregation induced emission” (AIE) CPs in sensing of biomolecules and bioimaging, these polymers should be soluble/dispersible in aqueous medium. Unfortunately, most of the CPs are hydrophobic in nature.…”

“…In the last decade, conjugated polymers (CPs) with an alternating array of donor (D) and acceptor (A) in the polymer backbone have attracted their applications in bioimaging, 1,2 biosensing, 3 photodynamic therapy, 4 lightemitting diodes, 5,6 solar cells, 7 thin-film transistors, 8,9 and explosive sensors. 10−12 The highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) energy levels could be easily controlled by choosing the appropriate electron-rich (donor) and electron-deficient (acceptor) moieties in the polymer backbone to tune the absorption and emission wavelengths.…”