Conjugated linoleic acid accelerates weight loss and improves anthropometric measures in overweight young adult males during weight loss program

Abstract

Background: With the increasing prevalence of obesity in Iraq, an increasing trend towards better physical fitness has emerged among young adults. At the same time, an increasing number of dietary supplements is offered to improve fitness and shed the extra weight. Conjugated linoleic acid (CLA) is commonly used for such purpose.
 Aim: The current study was designed to test if CLA can actually accelerate weight loss when combined with dieting and moderate exercise and to examine its effect on anthropometric measures of obesity.
 Subjects methods: Sixty young males enrolled willingly in the study and were put on a low-carbohydrate low-fat diet and moderate high intensity interval exercise (HIIT) program. Forty of them were given CLA (1000 mg/day) for 8 weeks while the remaining twenty served as control group. Body mass index (BMI), waist/hip ratio (WHR), sagittal abdominal diameter (SAD) and body adiposity index (BAI) were recorded as baseline and again after 4 and 8 weeks.
 Results: The CLA-treated group showed significantly greater reduction in all four measures by the end of the study. The control group had significant but less decrease in BMI SAD but not in WHR or BAI. The percent change difference between the first and second four weeks of the study also showed statistical difference among the two groups and for different measures. The most significant finding was that SAD dropped more rapidly during the first 4 weeks of the study indicating a preferential loss of visceral fat. Oppositely, WHR dropped during the second half of the study indicating loss of more abdominal fat stores.
 Discussion: Regardless of the mode of action of CLA, its accelerative effect in weight loss is augmented by the combination with dieting and physical activity. It also corresponds to the natural body preference to losing the more metabolically active visceral fat prior to switching to the loss of subcutaneous fat. Whether or not this effect is sustainable requires further study.

The effects of conjugated linoleic acid supplementation on anthropometrics and body composition indices in adults: a systematic review and dose–response meta-analysis

“…Of other note, CLA taken with other supplements, dietary restriction and increased physical activity may further promote the correction of anthropometric indices and body composition in obese individuals (112) . For example, combining CLA with γ -oryzanol significantly reduced body fat in overweight Korean female participants (82) .…”

Επίδραση Των Συνθηκών Παραγωγής, Συσκευασίας Και Λιανικής Πώλησης Στην Οξείδωση Των Λιπιδίων Και Των Πρωτεϊνών Καθώς Και Στη Σύνθεση Των Πολυακόρεστων Λιπαρών Οξέων Του Κεφαλοτυριού

“…Ζ πμνήβδζδ CLA ιε ηδκ ηνμθή ζε οπέναανμοξ ακενχπμοξ βζα 24 ιήκεξ είπε ςξ απμηέθεζια ζδιακηζηή ιείςζδ ημο ζςιαηζημφ αάνμοξ ηονίςξ ημοξ 6 πνχημοξ ιήκεξ (Gaullier et al 2005), εκχ άθθεξ ένεοκεξ έδεζλακ υηζ ζδιακηζηυηενδ ιείςζδ ημο αάνμοξ ηςκ ακενχπςκ επζηοβπάκεηαζ ιε ηδ πμνήβδζδ ημο trans-10, cis-12 CLA έκακηζ ημο cis-9, trans-11 CLA (Terpstra 2004). Βεθηίςζδ ηςκ ζςιαηζηχκ ακαθμβζχκ ηαζ ηαπφηενδ απχθεζα αάνμοξ παναηδνήεδηε ζε κεανμφξ άκδνεξ πμο ημοξ πμνδβήεδηε CLA (Akkila 2018). Σμ πμνδβμφιεκμ ιε ηδκ ηνμθή CLA έπεζ ζδιακηζηή επίδναζδ ζημ ιεηααμθζζιυ ηςκ ιοχκ (Kim et al 2016b), ζηδκ έηθναζδ ηςκ βμκζδίςκ πμο επδνεάγμοκ ημκ ζηεθεηυ (Chaplin et al 2015) ηαζ ακαζηέθθεζ ηδκ οπεναμθζηή εκαπμεήηεοζδ βθοημβυκμο ζημ ήπαν ηαζ ηδκ έηθναζδ ηςκ θζπμπαναβςβζηχκ βμκζδίςκ βζα ηδ δδιζμονβία de-novo θζπανχκ μλέςκ, ιε ιεβαθφηενδ δνάζδ ημο trans-10, cis-12 CLA έκακηζ ημο cis-9, trans-11 CLA (Maslak et al 2015).…”