Conjugated hypercrosslinked polymers imprinted with 3,5-dinitrosalicylic acid for the fluorescent determination of α-amylase activity

Yan, Ru-Yu; Lin, Wen-Hsin; Lu, Te‐Ling; Chen, Jian‐Lian

doi:10.1016/j.saa.2023.122383

Cited by 5 publications

(2 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, a fluorescence assay using molecular imprinting technology (MIP) was reported by Yan et al The accuracy and precision of measuring α-amylase activity were higher than that of the conventional UV-visible method, demonstrating the MIP method's potential for measurement accuracy [128].…”

Section: Molecularly Imprinted Polymer Methodsmentioning

confidence: 99%

Sensing of Digestive Enzymes—Diagnosis and Monitoring of Pancreatitis

Yin,

Cui,

Yang

et al. 2023

Chemosensors

View full text Add to dashboard Cite

This paper is a comprehensive review of the techniques for the detection of pancreatic enzymes, which are common biochemical indicators of pancreatitis, including amylase, trypsin, chymotrypsin, elastase, and lipase. Pancreatitis is a disease with self-digestion due to the abnormal activation of digestive enzymes in the pancreas. Hospitalization is often required due to the lack of convenient therapeutic agents. The main recent results are reported in this review, especially the techniques that enable portability and Point-of-Care testing (POCT). This is because timely diagnosis at the early stage and avoiding recurrence after recovery are the keys to treatment. It is also important to reduce the rate of misdiagnosis and to avoid overtreatment. Various detection methods are discussed, with particular attention given to the implementation of chemical sensing and probe design. The new sensing technology for digestive enzymes makes it possible to perform early screening for pancreatitis in remote areas or in one’s own home.

show abstract

Section: Molecularly Imprinted Polymer Methodsmentioning

confidence: 99%

Sensing of Digestive Enzymes—Diagnosis and Monitoring of Pancreatitis

Yin,

Cui,

Yang

et al. 2023

Chemosensors

View full text Add to dashboard Cite

show abstract

“…Conjugated polymers are finding ground in diverse applications, particularly in electronic devices based on organic materials, owing to their wide light-absorbing capacities, efficient photoluminescence, and good charge carrier mobilities. − Conjugated microporous polymers have, on the other hand, garnered prominence as a result of their stretched π-conjugated framework, extraordinary stability, simple synthesis, copious surface area, and favorable sorption of various gases. , While numerous structural families of conjugated polymers have been explored, such as linear, hyper-cross-linked, organic frameworks, and polycyclic aromatic hydrocarbons (PAHs), , a common challenge resides in their scarce solubility as a consequence of to their intrinsic rigidity. To address the solubility issue, which impedes the usage of these polymers in several applications that require solution-processed deposition techniques, researchers have introduced long and/or branched aliphatic side chains, which enhance the dissolution of the polymers in organic solvents .…”

Section: Introductionmentioning

confidence: 99%

Tröger’s Base-Enriched Conjugated Cyclopentannulated Copolymers: Prominent Adsorbents of CO₂, H₂, and Iodine

Shetty,

Baig,

Sengupta

et al. 2024

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Three copolymers with conjugated structures, PTB1−PTB3, were produced utilizing a palladium-catalyzed cyclopentannulation polymerization by reacting a specially designed diethynyl Troger's base surrogate with different dihalogenated polycondensed aromatic hydrocarbons. Brunauer, Emmet, and Teller nitrogen gas adsorption investigation revealed the surface areas of the copolymers, attaining ∼365 m 2 g −1 . Gas uptake studies demonstrated a considerable carbon dioxide uptake for PTB2 of 44.41 mg g −1 at 273 K and a promising H 2 gas uptake of 3.18 mg g −1 at 77 K. PTB1− PTB3 displayed a sizable iodine adsorption capacity, achieving 4000 mg g −1 , and mechanistic investigations demonstrated the prevalence of a pseudosecond-order kinetic model. Recyclability experiments proved the effective regeneration of the copolymers, even after performing several adsorption and desorption tests.

show abstract

A Simple and Eco‐Friendly Fluorescent Probe for α‐Amylase Detection Based on Hydroxyproply‐β‐Cyclodextrin‐Curcumin Inclusion Complex

Yan,

Guo,

et al. 2024

ChemistrySelect

View full text Add to dashboard Cite

Owing to the importance of α‐amylase in industry, it is necessary to develop a more simple and practical approach to measure α‐amylase activity. Herein, a fluorescence method was established for the detection of α‐amylase activity based on hydroxyproply‐β‐cyclodextrin‐curcumin inclusion complex (HP‐β‐CDs‐Cur). Curcumin was utilized as a signal probe, while hydroxyproply‐β‐cyclodextrin (HP‐β‐CDs) was employed both as a substrate of α‐amylase and the carrier of curcumin. α‐amylase is capable to hydrolyse α‐1,4‐glycosidic bond on the HP‐β‐CDs ring, facilitating the detection of its activity through the measurement of the decrease of fluorescence intensity caused by the release of curcumin into the aqueous. The results showed that there was a good linear relationship between fluorescence intensity and α‐amylase concentration in the range of 0.065~1.365 U mL−1, and the detection limit was 0.0065 U mL−1. The successful application of this method to evaluate the activities of multiple commercial α‐amylases underscores its robustness and reliability.

show abstract

Conjugated hypercrosslinked polymers imprinted with 3,5-dinitrosalicylic acid for the fluorescent determination of α-amylase activity

Cited by 5 publications

References 38 publications

Sensing of Digestive Enzymes—Diagnosis and Monitoring of Pancreatitis

Sensing of Digestive Enzymes—Diagnosis and Monitoring of Pancreatitis

Tröger’s Base-Enriched Conjugated Cyclopentannulated Copolymers: Prominent Adsorbents of CO₂, H₂, and Iodine

A Simple and Eco‐Friendly Fluorescent Probe for α‐Amylase Detection Based on Hydroxyproply‐β‐Cyclodextrin‐Curcumin Inclusion Complex

Contact Info

Product

Resources

About

Conjugated hypercrosslinked polymers imprinted with 3,5-dinitrosalicylic acid for the fluorescent determination of α-amylase activity

Cited by 5 publications

References 38 publications

Sensing of Digestive Enzymes—Diagnosis and Monitoring of Pancreatitis

Sensing of Digestive Enzymes—Diagnosis and Monitoring of Pancreatitis

Tröger’s Base-Enriched Conjugated Cyclopentannulated Copolymers: Prominent Adsorbents of CO2, H2, and Iodine

A Simple and Eco‐Friendly Fluorescent Probe for α‐Amylase Detection Based on Hydroxyproply‐β‐Cyclodextrin‐Curcumin Inclusion Complex

Contact Info

Product

Resources

About

Tröger’s Base-Enriched Conjugated Cyclopentannulated Copolymers: Prominent Adsorbents of CO₂, H₂, and Iodine