Conjonctival melanoma metastatic to the breast: a case report

Kharmoum, Saoussane; Mostafa, Mohamed; Benhammane, Hafida; Kharmoum, Jinane; Touri, Salima; Khadija, Setti; Bensouda, Y.; Boutayeb, Saber; Elghissassi, Ibrahim; Mrabti, Hind; Khannoussi, Bassma El; Sbitti, Yassir; Errihani, Hassan

doi:10.1186/1756-0500-7-621

Cited by 5 publications

(5 citation statements)

References 5 publications

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“…Synchronous metastasis occurs in 18% of patients with RCC at diagnosis and metachronous metastatic disease develop in 50% of RCC patients after nephrectomy [2] . RCC metastasis can occur in any organ, most commonly in the lungs, lymph nodes, bones, and liver [3] . Malignant tumors originating in the vagina are rare, and squamous cell carcinoma is the most common pathological type.…”

Section: Discussionmentioning

confidence: 99%

Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus

et al. 2022

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Rationale: Renal cell carcinoma (RCC) is the most common type of kidney cancer and is the second most common urologic neoplasm. Vaginal metastasis from RCC is extremely rare clinically. Patient concerns: A 56-year-old woman presented with intermittent vaginal bleeding that had persisted for 1 month. Enhanced computed tomography examination suggested a vaginal mass (3 × 2 × 2 cm), right kidney tumor (15 × 12 × 10 cm), and an inferior vena cava tumor thrombus. During gynecologic examination, the mass was necrotic and caused uncontrollable vaginal bleeding. Diagnoses: Based on clinical and imaging examinations and the pathology, she was diagnosed as vaginal metastasis from RCC. Interventions: The patient received percutaneous transcatheter arterial embolization to stop uncontrollable vaginal bleeding, and then treated with targeted therapy. Outcomes: Vaginal bleeding disappeared after interventional embotherapy. However, disease progressed, and the patient died 9 months later. Lessons: In cases of vaginal bleeding, the possibility of metastatic renal cell carcinoma should be considered. Percutaneous transcatheter arterial embolization is an effective and novel treatment for uncontrollable vaginal bleeding caused by vaginal metastasis of RCC.

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Section: Discussionmentioning

confidence: 99%

Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus

et al. 2022

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“… 3 – 6 In the present study, 30 cases of melanoma metastatic to the breast that were reported from 1995 to 2015, including the present case, were reviewed retrospectively. 7 – 23 The mean patient age was 54 years, and 87.1% of the patients were women. The most common primary sites of melanoma were the skin tissues of the trunk (28.6%, eight out of 28 patients) and head and face (28.6%, eight out of 28 patients).…”

Section: Discussionmentioning

confidence: 99%

Anorectal melanoma metastatic to the breast: a case report and review of the literature

Feng

Zhang

2016

OTT

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Melanoma develops from melanocytes and typically occurs on the skin and mucosa with a high degree of malignancy. Intensive local invasion and distant metastasis of melanoma result in poor patient prognosis, owing to frequent metastases to the lungs, bones, brains, and other parts of the body. In the present study, we report a case of anorectal melanoma in a 56-year-old woman who was admitted to our hospital because of local recurrence 9 months after local resection. She subsequently underwent radical surgery. Metastasis to the left breast occurred within 4 months after radical surgery. Metastasis of anorectal melanoma to the breast is very rare. In the present case report and literature review, we analyzed the clinical manifestation, diagnosis, and treatment of anorectal melanoma metastatic to the breast.

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“…Occult primary melanomas arising from a noncutaneous location could be a very unlikely source of a breast metastasis. 18…”

Section: Discussionmentioning

confidence: 99%

Phyllodes Tumor of the Breast With Malignant Melanoma Component

2015

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Phyllodes tumors of the breast display a wide variation in histological appearance and are classified into benign, borderline, and malignant categories based on a combination of histological parameters. These tumors may include a malignant heterologous component that is believed to originate through a process of multidirectional differentiation from a cancer stem cell. In these cases, the tumor is classified as a malignant phyllodes tumor. Among the heterologous elements that have been described in malignant phyllodes tumors are rhabdomyosarcoma, chondrosarcoma, osteosarcoma, liposarcoma and angiosarcoma. We present the first case of a phyllodes tumor with a malignant melanoma component in the breast of a 71-year-old lady, discussing the clinical implications of this diagnosis.

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Conjonctival melanoma metastatic to the breast: a case report

Cited by 5 publications

References 5 publications

Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus

Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus

Anorectal melanoma metastatic to the breast: a case report and review of the literature

Phyllodes Tumor of the Breast With Malignant Melanoma Component

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