Conjoined twins and opocephaly in guinea-pigs : 4 cases of congenital malformation

Abstract

189Summary A case of opocephaly in inbred guinea-pig strain 2jN and another in strain 13jN, a conjoined twin and an opocephaly concurrent with conjoined twins in the Dunkin-HartleyjFD strain are described. The incidence of congenital malformations in the inbred strain 2jN and strain 13jN was 0,0013 and 0,0073 % respectively. The incidence in the random-bred Dunkin-HartleyjFD strain was 0'0007%.Spontaneous congenital malformation of the guineapig have rarely been reported (Hoar, 1976). This is especially remarkable in view of the enormous numbers of guinea-pigs that are constantly being raised as laboratory animals. In a recent review of Case I. A conjoined twin Dunkin-HartleyjFD strain guinea-pig was found dead shortly after birth. The female twins had a single head with a broad face and 2 eyes. The upper abdomen was shared; the lower abdomen and hind quarters were separate and normally developed (Fig. ]). The fused thoracic cavities had 2 sterna, but only] normal respiratory system of larynx, trachea and lungs. There was a

Een asymmetrisch dubbelmonster geassocieerd met andere congenitale afwijkingen bij een chihuahuapup

“…Mazullo et al (2007) described a case of incomplete caudal duplication in a puppy and Nottidge et al (2007) described a case of monocephalus thoracophagus tetrabrachius in a dog. Other domestic species in which conjoined twinning has been reported include cattle (Arthur, 1956;Seebaransingh et al, 2007), sheep (Dennis, 1975), goats (Otiangi-Owitis et al, 1997), pigs (McManus et al, 1994Selby et al, 1972), cats (Seavers, 2009) and guinea pigs (Hong et al, 1977). Non-domestic animals in which conjoined twinning has been reported include the black rat (Rattus rattus) and the European hedgehog (Erinaceus europaeus) (Kompanje, 2005).…”

Conjoined Twins in Guinea Pigs: A Case Report

“…Genetic and environmental factors are considered to be the main causes of the development of conjoined twins. The overall etiology of the formation of conjoined twins is still unclear [ 9 , 10 ].…”

“…Hong et al [ 10 ] described two cases of conjoined twins in guinea pigs at a research center in the USA. The young were dead immediately after the birth.…”

Indirect Measurement for Body Surface Area of Cotton Rats

“…When renal or metabolic values are compared between two species of animals, they are expressed in terms of BSA [3]. Although cotton rats are used extensively in biomedical research [14], little information is available on the BSAs of these animals.…”

“…Subsequently, several equations have been reported for humans [12], and other animal species [1,3,6,9,10,11,131. However, these equations contain single or multiple K values (Mass coefficients) that vary with body weight.…”