Congruence between noise and plasticity in protein expression
Saburo Tsuru,
Chikara Furusawa
Abstract:Gene expression responds to various perturbations, such as mutations, environmental changes, and stochastic perturbations. The variability in gene expression levels differs among genes, influencing the availability of adaptive variants or mutants and thereby affecting nongenetic and genetic adaptations. Different types of variability are interdependent, suggesting global canalization/decanalization against different perturbations and a common underlying mechanism. Despite this, the relationship between plastic… Show more
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