Congruence between graduating nursing students’ self-assessments and mentors’ assessments of students’ nurse competence

Abstract

Quorum sensing (QS) is the process by which bacteria produce and detect signal molecules to coordinate their collective behavior. This intercellular communication is a relevant target for anti-biofilm therapies. Here we have optimized a screening-applicable assay to search for new quorum sensing inhibitors from natural compound libraries. In this system, QS is correlated with the production of violacein, which is directly controlled by the LuxI/LuxR system in Chromobacterium violaceum ATCC 31532. The parallel use of C. violaceum Tn5-mutant CV026, which depends on auto-inducer addition, allows simultaneous discrimination of compounds that act as quenchers of the AHL signal (quorum quenchers). The incorporation of a redox stain into the platform allowed further distinction between QS inhibitors, quorum quenchers and antibacterial compounds. A pilot screening was performed with 465 natural and synthetic flavonoids. All the most active compounds were flavones and they displayed potencies (IC 50 ) in the range of 3.69 to 23.35 µM. These leads were particularly promising as they inhibited the transition from microcolonies into mature biofilms from Escherichia coli and Pseudomonas aeruginosa strains. This approach can be very effective in identifying new antimicrobials posing lesser risks of resistance.

Nurse Competence Scale: a systematic and psychometric review

“…) and students’ assessments with mentors’ assessments in one study (Kajander‐Unkuri , Kajander‐Unkuri et al . ). Moreover, educators’ and managers’ assessments of NGNs’ competence were combined without NGNs’ self‐assessments in one study (Numminen et al .…”

“…) and nurse students’ assessments of their competence were, very optimistically, higher (VAS mean 66·2) than the assessments by their mentors (VAS mean 56·6) (Kajander‐Unkuri et al . ).…”

Effectiveness of a mobile cooperation intervention during the clinical practicum of nursing students: a parallel group randomized controlled trial protocol

“…) and to compare students’ and mentors’ assessments (Kajander‐Unkuri et al . ). In the previous study with student sample (Kajander‐Unkuri et al .…”

“…, Kajander‐Unkuri et al . ). In this study, competence is viewed as a learning outcome (Watson et al .…”

“…, Kajander‐Unkuri et al . , ), with the existing evidence derived from descriptive rather than experimental studies and mostly uncontrolled single‐cohort studies.…”