Congestive heart failure presence predicts delayed healing of foot ulcers in diabetes: An audit from a multidisciplinary high-risk foot clinic

Rhou, Yoon Ji Jina; Henshaw, Frances R; McGill, Margaret; Twigg, Stephen M.

doi:10.1016/j.jdiacomp.2015.02.009

Cited by 30 publications

(35 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other definitions were: percentage of ulcer area reduction; healing rate; and the pressure ulcer scale for healing score, which comprises of sub‐scores for ulcer size, tissue type, and exudate. Four studies considered more than one definition . Overall, almost half of the studies (20/42) were prospective, but only three investigated pressure ulcer healing .…”

Section: Resultsmentioning

confidence: 99%

“…Four studies considered more than one definition. 10,45,53,59 Overall, almost half of the studies (20/42) were prospective, but only three investigated pressure ulcer healing. 38,53,56 The most common statistical method used to analyse the data was regression analysis (30/42), and this was Cox regression in nine cases.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

See 1 more Smart Citation

Potential prognostic factors for delayed healing of common, non‐traumatic skin ulcers: A scoping review

Jenkins

Mohamed

Taylor

et al. 2019

International Wound Journal

View full text Add to dashboard Cite

Healing of non‐traumatic skin ulcers is often suboptimal. Prognostic tools that identify people at high risk of delayed healing within the context of routine ulcer assessments may improve this, but robust evidence on which factors to include is lacking. Therefore, we scoped the literature to identify which potentially prognostic factors may warrant future systematic reviews and meta‐analyses. We conducted electronic searches in MEDLINE and Embase to identify studies in English published between 1997 and 2017 that tested the association between healing of the three most common non‐traumatic skin ulcers encountered by health care professionals (venous leg, diabetic foot, and pressure ulcers) and patient characteristics, ulcer characteristics, and results from clinical investigations. We included 42 studies that investigated factors which may be associated with the healing of venous leg ulcers (n = 17), diabetic foot ulcers (n = 15), and pressure ulcers (n = 10). Across ulcer types, ulcer characteristics were most commonly reported as potential prognostic factors for healing (n = 37), including the size of the ulcer area (n = 29) and ulcer duration at first assessment (n = 16). A total of 35 studies investigated the prognostic value of patient characteristics (n = 35), including age (n = 31), gender (n = 30), diabetes (n = 22), smoking status (n = 15), and history of deep vein thrombosis (DVT) (n = 13). Of these studies, 23 reported results from clinical investigations as potential prognostic factors, with the majority regarding vessel quality. Age, gender, diabetes, smoking status, history of DVT, ulcer area, and ulcer duration at time of first assessment warrant a systematic review and meta‐analysis to quantify their prognostic value for delayed ulcer healing.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Potential prognostic factors for delayed healing of common, non‐traumatic skin ulcers: A scoping review

Jenkins

Mohamed

Taylor

et al. 2019

International Wound Journal

View full text Add to dashboard Cite

show abstract

“…a chronic wound of the foot or in the leg segment below the knee), the presence of HF with significant fluid accumulation in the lowest parts of the body can significantly affect the healing process, leading to delayed healing or worsening of the local condition. According to a study performed on 107 consecutive patients with foot ulcers and diabetes, the only independent predictive factor responsible for failure of healing, delayed healing at 12 weeks, or a reduced healing rate was the presence of congestive HF 24 . In the study performed by Xu et al .…”

Section: Local Leg Swelling Consequences In Heart Failure Patientsmentioning

confidence: 99%

Compression therapy for leg oedema in patients with heart failure

2020

View full text Add to dashboard Cite

The presence of chronic heart failure (CHF) results in a significant risk of leg oedema. Medical compression (MC) treatment is one of the basic methods of leg oedema elimination in patients with chronic venous disease and lymphedema, but it is not routinely considered in subjects with CHF-related swelling. In the study, an overview of the current knowledge related to the benefits and risk of using MC in the supportive treatment of leg oedema in CHF patients is presented. The available studies dedicated the comprehensive management of leg swelling using MC in CHF patients published in the English language literature till December 2019 were evaluated in term of the treatment efficacy and safety. In studies performed on CHF populations, manual lymphatic drainage, MC stocking, multilayer bandaged, as well as intermittent pneumatic compression or electric calf stimulations were used. The current evidence is based on non-randomized studies, small study cohorts, as well as very heterogenous populations. The use of the intermittent pneumatic compression in CHF patients significantly increases the right auricular pressure and mean pulmonary artery pressures as well as decreases systemic vascular resistance in most patients without the clinical worsening. The transient and rapid increase in the human atrial natriuretic peptide, after an application of the MC stocking in New York Heart Association (NYHA) class II patients was observed without clinical exacerbation. An application of the multilayer bandages in NYHA classes III and IV patients lead a significant increase in the right arterial pressure and lead to transient deterioration of the right and the left ventricular functions. In the manual lymphatic drainage study, aside from expected leg circumference reduction, no clinical worsening was observed. In a pilot study performed in a small cohort of CHF patients, electrical calf stimulation use resulted in a reduction in the lean mass of the legs without cardiac function worsening. The use of local leg compression can be considered stable CHF patients without decompensated heart function for both CHF-related oedema treatment and for treatment of the concomitant diseases leading to leg swelling occurrence. The use of MC in more severe classes of CHF (NYHA III and IV) should be the subject of future clinical studies to select the safest and most efficient compression method as well as to select the patients who benefit most from this kind of treatment.

show abstract

“…Cardiac component plays a role as well. Hence, it has been shown that heart failure is predictive for the delayed healing of diabetic foot ulcers being strongly associated with poor prognosis [108,109]. Further, heart failure is an independent risk factor for venous leg ulcers [110].…”

Section: Cardio-vascular Disease Is Critical For Wh and Follow-up Casmentioning

confidence: 99%

Impaired wound healing: facts and hypotheses for multi-professional considerations in predictive, preventive and personalised medicine

Avishai¹,

2017

View full text Add to dashboard Cite

Whereas the physiologic wound healing (WH) successfully proceeds through the clearly defined sequence of the individual phases of wound healing, chronic non-healing wounds/ulcers fail to complete the individual stages and the entire healing process. There are many risk factors both modifiable (such as stress, smoking, inappropriate alcohol consumption, malnutrition, obesity, diabetes, cardio-vascular disease, etc.) and non-modifiable (such as genetic diseases and ageing) strongly contributing to the impaired WH. Current statistics demonstrate that both categories are increasingly presented in the populations, which causes dramatic socio-economic burden to the healthcare sector and society at large. Consequently, innovative concepts by predictive, preventive and personalised medicine are crucial to be implemented in the area. Individual risk factors, causality, functional interrelationships, molecular signature, predictive diagnosis, and primary and secondary prevention are thoroughly analysed followed by the expert recommendations in this paper.

show abstract

Congestive heart failure presence predicts delayed healing of foot ulcers in diabetes: An audit from a multidisciplinary high-risk foot clinic

Cited by 30 publications

References 36 publications

Potential prognostic factors for delayed healing of common, non‐traumatic skin ulcers: A scoping review

Potential prognostic factors for delayed healing of common, non‐traumatic skin ulcers: A scoping review

Compression therapy for leg oedema in patients with heart failure

Impaired wound healing: facts and hypotheses for multi-professional considerations in predictive, preventive and personalised medicine

Contact Info

Product

Resources

About