Congestive heart failure in children with atrial septal defect

Weinberg, Milton; Miller, Robert A.; Hastreiter, Alois R.; Raffensperger, John G.; Fell, Egbert H.; Bucheleres, H.G.

doi:10.1016/s0022-5223(19)43276-5

Cited by 16 publications

(3 citation statements)

References 2 publications

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“…While patients with defects in the oval fossa are typically held to be asymptomatic in childhood, infants are often symptomatic. [3][4][5][14][15][16][17][18][19] Our data supports this belief, with almost nine-tenths of our patients being asymptomatic, while four-fifths of those presenting in cardiac failure did so at ages lower than 1 year.…”

Section: Kaplan-meier Curve Showing the Proportion Of Defects Remainisupporting

confidence: 79%

Spontaneous closure of atrial septal defects within the oval fossa

2004

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Section: Kaplan-meier Curve Showing the Proportion Of Defects Remainisupporting

confidence: 79%

Spontaneous closure of atrial septal defects within the oval fossa

2004

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“…Some infants with isolated secundum ASD fail to thrive and require early surgery. 1,3,5,6,10,11 Most of those who present early are symptomatic and have a wide variety of murmurs. Interestingly, a large number of these patients had dysmorphic features.…”

Section: Discussionmentioning

confidence: 99%

“…Usually, patients do not present clinically in the first year of life. [1][2][3][4][5][6] Closure of an isolated ASD in infancy is rare and only a few reports have described small groups of patients needing surgical closure in the first year of life. 1,2,[7][8][9] The outcome in these reports varies considerably.…”

Section: Introductionmentioning

confidence: 99%

Closure of Isolated Secundum Atrial Septal Defects in Infancy

Iyer

Hoschtitzky

Jacobs

et al. 2000

Asian Cardiovasc Thorac Ann

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Between 1965 and 1995, 552 patients underwent closure of isolated secundum atrial septal defect, of whom 24 (4.3%) were infants with a mean age of 238.5 ± 13.8 days (range, 90 to 348 days). Mean weight was 6 ± 0.3 kg (range, 3.5 to 9 kg). Twenty-two had noted failure to thrive and 13 had chest infections. Direct closure was carried out in 20 and 4 underwent patch closure. There were 3 (12.5%) early deaths (intraoperatively, 5 hours, and 2 days postoperatively). Three patients had pulmonary hypertension with pulmonary arterial to systemic arterial pressure ratios of 0.74 to 0.83 preoperatively. Of 21 survivors, 13 were extubated within 24 hours and 8 within 72 hours of surgery. Mean hospital stay was 16.2 ± 8.2 days. There were 2 late deaths; one from pneumonia at 177 days postoperatively and another patient with a severe neuromuscular disorder who could not be extubated, died 328 days postoperatively. We concluded that some infants require early surgery and an atrial septal defect can be closed safely in infancy but the risk increases in patients with pulmonary vascular disease. The etiology of pulmonary vascular disease in such patients remains unclear.

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Atrial Septal Defects That Present in Infancy

Mahoney¹

1986

Arch Pediatr Adolesc Med

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Congestive heart failure in children with atrial septal defect

Cited by 16 publications

References 2 publications

Spontaneous closure of atrial septal defects within the oval fossa

Spontaneous closure of atrial septal defects within the oval fossa

Closure of Isolated Secundum Atrial Septal Defects in Infancy

Atrial Septal Defects That Present in Infancy

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