Congestive heart failure caused by transvenous pacemaker lead prolapse and associated right ventricular outflow tract obstruction in a dog

Djani, Dylan M.; Coleman, Amanda E.; Rapoport, G.; Schmiedt, Chad W.; Layher, John W.; Thomason, Justin D.

doi:10.1016/j.jvc.2016.05.003

Cited by 5 publications

(4 citation statements)

References 16 publications

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“…. 331–364 Most were case series or single case reports (LOE 5), and 1240 dogs were described, of which 60 had suspected or confirmed thrombosis (5%). Two studies were experimental (LOE 3) but of poor quality 336,361 .…”

Section: Peco Question: Transvenous Pacemaker (Dogs)mentioning

confidence: 99%

“…The remaining supportive studies included 17 dogs with thrombosis following transvenous pacemaker implantation, typically in the cranial vena cava, some of which were fatal. Some studies reported comorbidities, including trauma, PLN and infection, that could have contributed to the risk of thrombosis 244,331,338,344,345,357,358,360,362,363 . Four publications (LOE 5) were considered neutral to the PECO question either due to lack of follow‐up, multiple possible causes for thrombosis, or reasons other than the presence of a pacemaker that were deemed likely to result in thrombosis (e.g., stenosis) 334,337,339,346 …”

Section: Peco Question: Transvenous Pacemaker (Dogs)mentioning

confidence: 99%

“…Overall, 13 studies (1 LOE 3, 12 LOE 5) support the PECO question and suggest an association between transvenous pacemakers and thrombosis in dogs. 244,331,335,338,341,344,345,355,357,358,[360][361][362] The one LOE 3 report that supported the PECO question was a retrospective case series of 101 dogs that had polyurethane insulated transvenous pacemaker leads implanted. 361 These pacemakers were in place for between 10 days and 13 years before euthanasia and postmortem examination.…”

Section: Evidence Summarymentioning

confidence: 99%

“…Some studies reported comorbidities, including trauma, PLN and infection, that could have contributed to the risk of thrombosis. 244,331,338,344,345,357,358,360,362,363 Four publications (LOE 5) were considered neutral to the PECO question either due to lack of follow-up, multiple possible causes for thrombosis, or reasons other than the presence of a pacemaker that were deemed likely to result in thrombosis (e.g., stenosis). 334,337,339,346 Eighteen studies (1 LOE 3 good, 17 LOE 5 good-fair) were judged to be neutral to the PECO question based on long-term follow-up of dogs after pacemaker implantation without reports of thrombotic complications.…”

Section: Evidence Summarymentioning

confidence: 99%

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2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1‐ Defining populations at risk

deLaforcade

Bacek

Blais

et al. 2022

J Vet Emergen Crit Care

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Objectives: To expand the number of conditions and interventions explored for their associations with thrombosis in the veterinary literature and to provide the basis for prescribing recommendations. Design: A population exposure comparison outcome format was used to represent patient, exposure, comparison, and outcome. Population Exposure Comparison Outcome questions were distributed to worksheet authors who performed comprehensive searches, summarized the evidence, and created guideline recommendations that were reviewed by domain chairs. The revised guidelines then underwent the Delphi survey process to reach consensus on the final guidelines. Diseases evaluated in this iteration included heartworm disease (dogs and cats), immune-mediated hemolytic anemia (cats), protein-losing nephropathy (cats), protein-losing enteropathy (dogs and cats), sepsis (cats), hyperadrenocorticism (cats), liver disease (dogs), congenital portosystemic shunts (dogs and cats) and the following interventions: IV catheters (dogs and cats), arterial catheters (dogs and cats), vascular access ports (dogs and cats), extracorporeal circuits (dogs and cats) and transvenous pacemakers (dogs and cats).Results: Of the diseases evaluated in this iteration, a high risk for thrombosis was defined as heartworm disease or protein-losing enteropathy. Low risk for thrombosis was defined as dogs with liver disease, cats with immune-mediated hemolytic anemia, protein-losing nephropathy, sepsis, or hyperadrenocorticism. Conclusions:Associations with thrombosis are outlined for various conditions and interventions and provide the basis for management recommendations. Numerous knowledge gaps were identified that represent opportunities for future studies.

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Section: Peco Question: Transvenous Pacemaker (Dogs)mentioning

confidence: 99%

Section: Peco Question: Transvenous Pacemaker (Dogs)mentioning

confidence: 99%