Congenitally corrected transposition of the great arteries

Congenitally Corrected Transposition of the Great Arteries

“…It is this right-sided coronary that bifurcates into the anterior descending artery, which lies in the interventricular groove, and the circumflex branch that runs posterior to the heart through its course in the right AV sulcus. Additional rare anomalies have been described in which both main coronaries arise from a single ostia or one main coronary gives rise to the other (i.e., anterior descending off the right coronary artery) (Hornung & Calder, 2010;Ismat et al, 2002). The cardiac veins seem to correspond to ventricular and coronary anatomy as described in a pathological series by Bottega et al (2009).…”

“…Furthermore, as the TV is subjected to systemic pressures, even normally formed valves display progressive regurgitation with age. Less common defects occurring in association with ccTGA include atrial septal defect, patent ductus arteriosus, pulmonary atresia, double-outlet RV, aortic regurgitation, mitral valve abnormalities, and subaortic stenosis (Graham & Markham, 2010;Hornung & Calder, 2010;Van Praagh et al, 1998). …”

Midterm evaluation of echocardiographic examination, cardiac catheterization findings and surgical results of patients with congenitally corrected transposition of great arteries: A single center experience

“…The persistence of the morphologic right ventricle as systemic ventricle had resulted in progressive tricuspid regurgitation and ended up with systemic ventricular dysfunction. In terms of long-term results, it was disappointing (1,6,20) . Lundstom et al reported premature deaths in 11 out of 51 cases.…”

“…Several studies have estimated the incidence as 2.6 to 8.6 per 1000 live births (1,9) . A variable clinical course and long-term follow-up results have been reported in cc-TGA patients, which are heterogeneous group of patients because of having a rare anomaly and the presence of numerous accompanying anomalies (9,11) .…”

“…Congenitally corrected transposition of the great arteries (cc-TGA), also termed as double discordance and ventricular inversion or physiologically corrected transposition of the great arteries, is a rare defect characterized by the combination of atrioventricular and ventriculoarterial discordance, which comprises about 0.5% of all congenital cardiac anomalies (1) . There is a heterogeneous group of patients and highly variable clinical course associated with the presence and severity of accompanying abnormalities such as ventricular septal defect (VSD), pulmonary stenosis (PS)/atresia, Ebstein-like malformation of the tricuspid valve (2) .…”