Congenital vascular malformation associated with multiple cranial, vertebral and upper limb skeletal abnormalities

Marsden, Nick; Shokrollahi, Kayvan; K, Maw; Sierakowski, Adam; Bhat, FA; Mathur, Bhagwat

doi:10.1308/147870810x12699662980114

Cited by 5 publications

(1 citation statement)

References 4 publications

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“…Servelle in the 1940s and 1950s described 80 cases of Klippel-Trenaunay syndrome, of which fibrous bands or aberrant arteries were found to compress deep venous channels resulting in varicosity in 79 of the patients; however, in one deviant case, no obstructing lesion was present and instead agenesis was present [3]. His research in combination with that of Martorell was later felt to potentiate a third clinical entity characterized by limb hypertrophy, varicose veins, and capillary malformations but osseous hypotrophy and limb foreshortening [4,5].…”

Section: Discussionmentioning

confidence: 99%

Cervical dural arteriovenous malformation and large epidural venous varices in a rare adult presentation of congenital vascular bone syndrome

Garg¹,

Manjila²,

Corriveau³

et al. 2015

Clinical Imaging

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Section: Discussionmentioning

confidence: 99%

Cervical dural arteriovenous malformation and large epidural venous varices in a rare adult presentation of congenital vascular bone syndrome

Garg¹,

Manjila²,

Corriveau³

et al. 2015

Clinical Imaging

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Green Light‐Based Photobiomodulation with an Implantable and Biodegradable Fiber for Bone Regeneration

Jiang

Líu

et al. 2020

Small Methods

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Photobiomodulation (PBM) has recently started to gain popularity in clinical therapeutics. Visible light, in particular, plays a critical role in osteogenesis modulation. However, the limited penetration depth of visible light in biological tissues has constrained the application of this technology in vivo. Herein a green light‐based PBM technique with implantable and biodegradable poly(L‐lactic acid) & poly(L‐actic‐co‐glycolic acid) optical fibers to achieve accelerated bone regeneration is explored. Facilitated with experimental characterizations as well as numerical simulations, optical and thermal behaviors of fibers operated in the biological environment are understood. The optical regulation of bone regeneration is systematically studied both in vitro and in vivo. Under green light irradiation, biochemical activities of bone marrow‐derived mesenchymal stem cells and their expression of osteogenic‐related factors are significantly elevated. By introducing green light into defective bone structures via fibers in a rodent model, the process of bone regeneration and repair is accelerated. Furthermore, fibers exhibit ideal biocompatibility with both cultured cells and living tissues and undergo complete degradation in vivo after ≈1 month. Assisted with degradable optical materials and devices, such as photobiomodulation technique provides a promising solution to tissue regeneration in various biomedical applications.

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Epidemiology of Vascular Malformations

Khanna¹,

Khanna

2021

Vascular Malformations

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Congenital vascular malformation associated with multiple cranial, vertebral and upper limb skeletal abnormalities

Cited by 5 publications

References 4 publications

Cervical dural arteriovenous malformation and large epidural venous varices in a rare adult presentation of congenital vascular bone syndrome

Cervical dural arteriovenous malformation and large epidural venous varices in a rare adult presentation of congenital vascular bone syndrome

Green Light‐Based Photobiomodulation with an Implantable and Biodegradable Fiber for Bone Regeneration

Epidemiology of Vascular Malformations

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