Congenital pyloric atresia. A report on a successfully treated case and existing research.

Abstract

Congenital pyloric atresia is a rare malformation that occurs with a frequency of about one per million births. One hundred fifty-one cases of the anomaly have been reported including 28 cases in Japan. This is a report on an additional case of membranous atresia that was treated successfully by incision of the diaphragm with pyloroplasty. The familial occurrence in siblings and the association of the abnormality with hereditary epidermolysis bullosa suggests a genetic etiology. Treatment should be surgical and the choice of an operative procedure should depend on the anatomical type of atresia. Excision or incision of the diaphragm with pyloroplasty and gastroduodenostomy offer the most promising opportunity for successful treatment. The mortality rate is 49.3% and the prognosis is dependent upon such factors as early diagnosis, the appropriate operative procedure, the extent of prematurity of the infant and association of other congenital anomalies or compli cations.

Prenatal Diagnosis of Prepyloric Diaphragm: A Case Report

“…Kodoma et al reported 38.8% mortality rate has been found in children with congenital web or diaphragm and mortality rate goes up if there are other gastrointestinal anomalies (92.1%) 11 . Affected neonates usually die due to respiratory distress, aspiration pneumonia, metabolic alkalosis resulting from persistent vomiting, and even gastric perforation 11 . Meckel's Diverticulum and malrotation have been found as associated anomalies during surgery in our case.…”