Congenital Prepubic Sinus: A Variant of Dorsal Urethral Duplication Suggested by Immunohistochemical Analysis

Huang, Chao‐Cheng; Wu, Wang-Hseng; Chai, Chee‐Yin; WU, TZYY-CHOOU; Chuang, Jiin‐Haur

doi:10.1016/s0022-5347(05)65711-4

Cited by 29 publications

(17 citation statements)

References 10 publications

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“…Multiple theories have been proposed to explain the embryological aetiology for congenital prepubic sinus, among which the theory suggesting that it is a variant of urethral duplication predominates 7. In our case, patient’s anomaly was similar to the type IA variant of Effman’s classification suggesting it to be a variant of epispadiac urethral duplication.…”

Section: Discussionmentioning

confidence: 51%

Congenital prepubic sinus (an epispadiac variant of dorsal urethral duplication) with dorsal penile curvature in an adult man: a rare association

Aeron¹,

Goel

Singh

et al. 2017

BMJ Case Reports

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Urethral duplication is among a very rare congenital disorder with multiple anatomical variants reported. Urethral duplication of complete type is usually diagnosed during childhood with urinary incontinence or double urinary stream as common presentation. However, patients with incomplete urethral duplication usually present with intermittent mucous discharge from the accessory urethral opening. A 20-year-old man presented to us with intermittent mucous discharge from the accessory opening along with dorsal penile curvature making sexual intercourse very difficult. The epispadiac urethral tract with proximal fibrous tract was excised, and the dorsal penile curvature was corrected by ventral plication, implicating that the fibrous cord may be the causative factor for the development of dorsal curvature.

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Section: Discussionmentioning

confidence: 51%

Congenital prepubic sinus (an epispadiac variant of dorsal urethral duplication) with dorsal penile curvature in an adult man: a rare association

Aeron¹,

Goel

Singh

et al. 2017

BMJ Case Reports

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“…However, Huang et al . reported that the immunohistochemical study revealed the lining epithelium was transitional proximally and squamous distally in five patients with congenital prepubic sinus and reinforced the theory that congenital prepubic sinus is a variant form of dorsal urethral duplication 4 …”

Section: Discussionmentioning

confidence: 67%

Congenital prepubic sinus: A variant of dorsal urethral duplication (Stephens type 3)

et al. 2005

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A 3-year-old boy was admitted for yellowish discharge from a tiny opening in the midline prepubic area on the dorsal base of the penis. No other symptom related to the genitourinary tract was noted.Sinuousgraphy showed a non-communicating sinus tract with the urinary tract. At surgical exploration, through a diamond-shaped incision, a 4.5 cm-long sinus was found that ended blindly as a fibrous cord at the anterior surface of the pubic symphisis. Histologically, it was lined by stratified squamous epithelium and surrounded by bundles of smooth muscle and collagen. According to Stephens' classification, the sinus appears to be a variant of dorsal urethral duplication of Stephens type 3.

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“…Urethral duplication most often occurs in the sagittal plane, and if blind-ending is referred to as a pre-pubic sinus [2]. Bladder duplication is most often complete versus incomplete, in which the bladders are separate entities and drained by separate urethras [3].…”

Section: Resultsmentioning

confidence: 99%

Combined robotic and open approach to excision of accessory bladder and urethral triplication

Bowen

Glaser

Bush

et al. 2015

Journal of Pediatric Urology

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Congenital Prepubic Sinus: A Variant of Dorsal Urethral Duplication Suggested by Immunohistochemical Analysis

Abstract: The existence of transitional epithelium in the proximal part of the sinus and presence of smooth muscle bundles around it reinforce the theory that congenital prepubic sinus is a variant form of dorsal urethral duplication.

Cited by 29 publications

References 10 publications

Congenital prepubic sinus (an epispadiac variant of dorsal urethral duplication) with dorsal penile curvature in an adult man: a rare association

Congenital prepubic sinus (an epispadiac variant of dorsal urethral duplication) with dorsal penile curvature in an adult man: a rare association

Congenital prepubic sinus: A variant of dorsal urethral duplication (Stephens type 3)

Combined robotic and open approach to excision of accessory bladder and urethral triplication

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