Congenital pemphigus syphiliticus

Hong-mei, Tang; Zhao, Peng; Chen, Jing; Liu, Lichang

doi:10.1016/j.ijid.2016.05.031

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…El personal médico asistencial debe estar habituado a las manifestaciones clínicas de la SC, comunes en otrora época, sin embargo, con la mejora en la calidad de atención, el uso de penicilina, se observan (14) con menor frecuencia .…”

Section: Discussionunclassified

Pénfigo sifilítico: reporte de un caso.

Mejía

Carlos

2021

Pediatr (Asunción).

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La sífilis congénita (SC) es el resultado de la infección producida por el Treponema pallidum al feto, en una madre con sífilis gestacional (SG). La enfermedad puede ser asintomática en el 60% de los recién nacidos (RN) afectados, siendo además difícil de diagnosticar clínica e histológicamente, porque tanto sus patrones clínicos como histológicos, pueden imitar otras enfermedades dermatológicas del RN. Siendo la SC una enfermedad prevenible, siguen presentándose casos con manifestaciones clínicas severas. Presentamos el caso de un RN con SC de presentación grave desde el nacimiento, con manifestaciones cutáneas que incluyeron múltiples lesiones tipo vesículas y bulas, con zonas hemorrágicas y áreas denudadas con maceración, descamación y costras, de predominio en palmas y plantas, compatibles con pénfigo sifilítico. Reconocer las diversas manifestaciones clínicas, en especial las cutáneas, es fundamental para realizar un diagnóstico oportuno de SC en RN y lactantes. Conflicto de interés: Los autores declaran no poseer conflicto de interés Recibido: 11/10/2020 Aceptado:17/02/2021

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Section: Discussionunclassified

Pénfigo sifilítico: reporte de un caso.

Mejía

Carlos

2021

Pediatr (Asunción).

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“…Because the bullae are fragile and rapidly erode, denuded bullae and desquamation is the most likely clinical presentation, as in this case. In a PubMed search for “pemphigus syphiliticus,” “syphilis/syphilitic pemphigus,” “bullous syphilis,” “acral blister neonate,” and “congenital syphilis” filtering for Case Reports, fewer than 20 total other case reports of this bullous presentation were found since 1946, the beginning of PubMed indexing …”

Section: Discussionmentioning

confidence: 99%

“…In a PubMed search for "pemphigus syphiliticus," "syphilis/ syphilitic pemphigus," "bullous syphilis," "acral blister neonate," and "congenital syphilis" filtering for Case Reports, fewer than 20 total other case reports of this bullous presentation were found since 1946, the beginning of PubMed indexing. [7][8][9][10] In classic syphilography textbooks dating to 1869, the bullous presentation of congenital syphilis was regarded as common. 11,12 It was recognized in this era that, in adults, this blistering presentation "is almost always independent of syphilis," but in children, it "most frequently coexists with changes the syphilitic origin of which is indisputable."…”

Section: Discussionmentioning

confidence: 99%

A rare presentation of congenital syphilis: Pemphigus syphiliticus in a newborn infant with extensive desquamation of the extremities

Wang

Chambers

Silverstein

2018

Pediatric Dermatology

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Congenital syphilis is an infection transmitted from mother to fetus and can present with early but variable cutaneous manifestations. In rare situations, a bullous eruption known as pemphigus syphiliticus may develop. We present an unusual case of broad desquamation of the extremities in a newborn infant who was found to have congenital syphilis. Pemphigus syphiliticus should be considered in the differential diagnosis of neonatal bullous eruptions and erosions.

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