“…On the other hand, in a subgroup analysis of patients with two-ventricle Fontan, they found that the larger rudimentary ventricular end-diastolic volume/dominant ventricular enddiastolic volume ratio was associated with significantly higher dominant ventricular end-diastolic pressure and a significant decrease of maximum oxygen consumption (VO 2 max). 1 The findings of the study by Miwa and colleagues are in line with a number of recent studies that demonstrated again no advantage of having a larger rudimentary ventricle on Fontan outcomes. 2,3 These findings challenge the intuitive notion that having a larger rudimentary ventricle might be advantageous for adding additional squeezing power to the dominant ventricle; thus, a greater contribution to stroke volume.…”