Congenital Micropenis: Etiology And Management

Stancampiano, Marianna Rita; Suzuki, Kentaro; O’Toole, Stuart; Russo, Gianni; Yamada, Gen; Ahmed, S Faisal

doi:10.1210/jendso/bvab172

Cited by 10 publications

(8 citation statements)

References 145 publications

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“…Perhaps 2 cm may represent a more appropriate cutoff as an international standard while bearing in mind the regional and genetic differences in puberty. 9 In our study microphallus is detected below 5th percentiles according to age for example less than 27mm at the age of first 2 months. There is a significant relationship between hypogonadism and microphallus.…”

Section: Resultssupporting

confidence: 46%

Prevalence and Impact of External Genitourinary Anomalies among Children undergoing routine Circumcision

Ibrahim

Fahmy

Seddek

2023

Al-Azhar International Medical Journal

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Background: The knowledge of the incidence of congenital anomalies is important for planning health services in our country. It helps in planning the budget as well as measures for the management and the prevention of the disorders. It also helps to establish a program raising awareness of urogenital anomalies and their management. Aim of the study:The aim of this study is to evaluate the normal anthropometric value of the normal penis and to detect the prevalence and impact of external genitourinary anomalies among 3000 Egyptian children attending for nonmedical circumcision. Patients and Methods:The prospective multi centric study was done on 3000 male babies coming for routine circumcision in an outpatient clinic at Al Azhar university hospitals in the period from 2018 to 2021. All babies were examined and evaluated for the genitourinary parameters. Results: the study suggests normal anthropometric values of SPL , AGD, preputial length, meatal diameter according to age. The incidence of urogenital anomalies among studied children is about 18.4%. Conclusion:This study gives value reference and percentile curves for stretched penile length (SPL) , AGD, Preputial length, meatal diameter and glans closure length in healthy Egyptian males from the age of one day to 10 years

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Section: Resultssupporting

confidence: 46%

Prevalence and Impact of External Genitourinary Anomalies among Children undergoing routine Circumcision

Ibrahim

Fahmy

Seddek

2023

Al-Azhar International Medical Journal

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“…Outros 04 pacientes do sexo masculino realizaram o exame de cariótipo por apresentarem micropenis, uma condição rara que afeta os indivíduos do sexo masculino, com prelavência estimada em 0,6 a 1,2 casos por 10.000 nascidos vivos no Brasil, caracterizada por um pênis anormalmente pequeno, medindo menos de 2,5 desvios-padrão abaixo da média para a idade cronológica (Khadilkar & Mondkar, 2023;Stancampiano et al, 2022). As causas podem incluir anomalias genéticas ou hormonais e todos os 04 pacientes do estudo apresentaram cariótipo normal 46,XY, necessitando, portanto, de outros testes moleculares e bioquímicos para a descoberta da etiologia (Bearelly & Oates, 2019;Matsumoto & Anawalt, 2020b;Navarro-Cobos et al, 2020b).…”

Section: Resultsunclassified

Disorders of Sexual Development (DSD) in Piauí: an epidemiological study

Pereira¹,

Nascimento

et al. 2023

CLIUM

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Disorders of Sex Development (DSD) are congenital conditions in which the chromosomal, gonadal, or anatomical development of sex is atypical. DSD can occur due to variations in sex chromosomes or autosomes, in genes related to gonadal or genital development, or in alterations in hormone production by the reproductive organs. These conditions can range from common abnormalities such as cryptorchidism and hypospadias to rare and complex conditions such as complete sex reversal. This study analyzed the clinical and cytogenetic profile of individuals suspected of DSD who underwent karyotype testing in the state of Piauí from 2020 to 2022. Out of the 250 patients evaluated, 21% were suspected of having DSD, with a predominance of females (60%). Turner syndrome was the most common clinical suspicion, followed by ambiguous genitalia, Klinefelter syndrome, and micropenis. The results emphasize the importance of early diagnosis and psychological support for parents and individuals with DSD, aiming for appropriate treatment and the promotion of a healthy and satisfying life. Additionally, the study highlighted the need for the implementation of molecular tests to reach a conclusive diagnosis when DSD is not of chromosomal origin.

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“…The penis is typically small at birth, with an average stretched length of 3.5 cm in full-term newborn males. The penis may appear larger than expected due to increased adipose tissue, which is usually non-erect[ 16 ]. The foreskin is typically fused with the glans.…”

Section: Penile Developmentmentioning

confidence: 99%

Microphallus early management in infancy saves adulthood sensual life: A ‎‎comprehensive review ‎

Al-Beltagi,

Saeed,

Bediwy

et al. 2024

World J Clin Pediatr

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Microphallus/Micropenis is a rare condition with significant physical and psychological implications for affected individuals. This article comprehensively reviews micropenis, its etiology, epidemiology, and various treatment options. We conducted a thorough literature review to collect relevant information on micropenis and microphallus, as well as related disorders. Our primary databases were PubMed, Medline, and Google Scholar. We searched for articles published in English between 2000 and 2023. Our analysis included 67 review articles, 56 research studies, 11 case reports, one guideline, and one editorial. Our search terms included "microphallus", "micropenis", "congenital hypogonadotropic hypogonadism", "androgen insensitivity syndrome", "pediatric management of micropenis", "testosterone therapy", and "psychosocial implications of micropenis". We focused on diagnosing micropenis and related conditions, including hormonal assessments, medical and surgical treatment options, psychosocial and psychological well-being, sexual development of adolescents, and sociocultural influences on men's perceptions of penile size. Additionally, we explored parenting and family dynamics in cases of micropenis and disorders of sex development, implications of hormonal treatment in neonates, and studies related to penile augmentation procedures and their effectiveness. The article highlights the importance of early diagnosis and intervention in addressing the physical and psychological well-being of individuals with micropenis. Surgical procedures, such as penile lengthening and girth enhancement, and non-surgical approaches like hormonal therapy are explored. The significance of psychological support, education, and lifestyle modifications is emphasized. Early management and comprehensive care are crucial for individuals with micropenis, from infancy to adolescence and beyond. A multidisciplinary approach involving urologists, endocrinologists, and mental health professionals is recommended. Regular assessment of treatment effectiveness and the need for updated guidelines are essential to provide the best possible care. Healthcare professionals should prioritize early diagnosis, and neonatologists should measure stretched penile length in neonates. A collaborative effort is needed among professionals, parents, and affected individuals to create a supportive environment that recognizes worth beyond physical differences. Continuous research and evidence-based updates are crucial for improving care standards.

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Congenital Micropenis: Etiology And Management

Cited by 10 publications

References 145 publications

Prevalence and Impact of External Genitourinary Anomalies among Children undergoing routine Circumcision

Prevalence and Impact of External Genitourinary Anomalies among Children undergoing routine Circumcision

Disorders of Sexual Development (DSD) in Piauí: an epidemiological study

Microphallus early management in infancy saves adulthood sensual life: A ‎‎comprehensive review ‎

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