Congenital malformations at birth in 7,922 consecutive deliveries at Patan Hospital, Nepal

Ansari, Imran; Rajbhandari, Rateena; Chalise, Shiva Prasad Sharma; Shah, Ganesh; Maskey, Pratistha; Maharjan, Rashmila; Yadav, R. N.; manandhar, B; Ansari, Rahil

doi:10.3126/jpahs.v1i2.16636

Cited by 7 publications

(12 citation statements)

References 2 publications

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“…[2][3][4] In a study of 10 months duration from our institute reported it at 0.81%. 5 In our study, CNS were more common, with higher frequencies of anencephaly followed by hydrocephalus and meningomyelocele. Folic acid is given once a couple plan baby and through the first trimester of pregnancy to reduce such central nervous system anomalies.…”

Section: Discussionsupporting

confidence: 47%

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Congenital anomalies in antenatal ultrasound scan at a tertiary care teaching hospital

Shrestha

Dwa²,

Jaiswal³

et al. 2018

J Patan Acad Health Sci

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Introductions: Early detection of congenital fetal anomalies by ultrasonography (USG) helps to identify the severity and termination of pregnancy in severe cases. Anomalies cause significant perinatal morbidity and mortality. Aim of this study was to analyse real-time USG detection of prenatal anomalies. Methods: This was a cross-sectional descriptive study of fetal anomalies detected during 2nd and 3rd trimester antenatal USG scan done from 2011 to 2015, in Patan Hospital. Age of mother, parity, gestational age when anomalies detected and, anomalies of previous child, use of folic acid were analysed. Descriptive analysis was done. Results: There were 35,571 deliveries in four years period with 134 (0.37%) congenital anomalies, 99 (79.2%) detected during antenatal USG during 2nd and 3rd trimester. Among 99 anomalies, 29 (29.29%) were detected before 22 weeks. Central nervous system (CNS) anomalies were 47, gastrointestinal 23, renal 12, skin and fetal compartment 8 and rest were less common. Young mothers of less than 30 years were 109 (81.34%) and primi were 85 (63.4%). Conclusions: Antenatal ultrasound can detect fetal anomalies in 2nd and 3rd trimester with higher frequencies belonging to the central nervous system followed by gastrointestinal tract anomalies and renal.

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Section: Discussionsupporting

confidence: 47%

“…Central Nervous,2 Gastrointestinal,3 Renal,4 Skin and Fetal Compartment,5 Respiratory,6 Musculoskeletal, 7 Cardiovascular 8 Lymphatic)…”

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confidence: 99%

Congenital anomalies in antenatal ultrasound scan at a tertiary care teaching hospital

Shrestha

Dwa²,

Jaiswal³

et al. 2018

J Patan Acad Health Sci

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“…5 The rate was still higher than another study conducted in Patan hospital in the year 2014 (0.8%). 6 However, the prevalence rate of congenital malformations obtained in our study is similar to the findings of Herbert A Obu, et al (2.8%). 7 …”

Section: Discussionsupporting

confidence: 92%

“…Congenital malformations of the central nervous system were also the commonest birth defect is a study done in North of Iran. 14 Malformations of the musculoskeletal system were observed to be the commonest in a study conducted by Sharma I 4 in Western Regional Hospital, Pokhara, Nepal, Ansari, et al 6 at Patan Hospital and Baruah 8 in Northeast India.…”

Section: Discussionmentioning

confidence: 94%

Prevalence of Congenital Malformations among Babies Delivered at a Tertiary Care Hospital

Shrestha

2020

J Nepal Med Assoc

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Introduction: Congenital malformations have emerged as a major cause of stillbirths and neonatalmortality. It is a common cause of morbidity and mortality not only in the newborn but also in childhoodand beyond. The objective of this study was to find the prevalence of congenital malformation at birth. Methods: The descriptive cross-sectional study was conducted among 2456 live births in KathmanduMedical College and Teaching Hospital from April 2017 to March 2018 after obtaining ethicalapproval from the institutional review committee (Ref no. 08052017). A convenient sampling methodwas applied. All the live-born babies delivered in this hospital during the study period were clinicallyexamined for the presence of congenital anomalies. All malformations were classified accordingto the International Classification of Diseases-10 classification. The mothers of the newborns withcongenital malformations were interviewed in a predesigned proforma. Statistical analysis was doneusing statistical package for the social sciences version 20. Results: Out of 2456 examined live births, congenital malformations were observed in 66 cases.The prevalence of congenital malformation was 66 (2.6%) at 95% confidence interval (4.19-1.98) oftotal live births. The genitourinary system was the most common system involved with congenitalmalformations being 16 (24.2%), followed by musculoskeletal system 14 (21.2%), and cardiovascularsystem 12 (18.2%). Conclusions: Congenital malformation plays a major role in the mortality and morbidity of neonatesas well as children. The genitourinary system was the most common system involved.

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“…This rate is slightly lower than the earlier report published 15 years ago from the hospital of 1.3% on 5739 deliveries; 5 most probably it is due to increasing number of the rate of birth. This rate was higher in comparison to other hospital, reported 0.36% in Maternity Hospital ,Thapathali, 7 0.42% in Western Regional Hospital, 9 Pokhara and 0.8% in Patan hospital, 6,8 Kathmandu, due to increased referral for congenital anomalies and high risk pregnancy, for better perinatal and maternal outcome, and it increased unbooked cases to this institution and likewise increase in number of anomalous baby. Our study has a higher incidence of congenital anomalies among male babies 0.63% than female babies 0.51%.…”

Section: Discussionmentioning

confidence: 54%

Incidence of Congenital Fetal Malformation Abnormalities in Tribhuban University, Teaching Hospital, Kathmandu, Nepal: a Hospital Based Study

Bajracharya

Rajbhandari²,

Gurung³

et al. 2021

Europasian J Med Sci.

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Background : Birth defects are defined as abnormalities of structure or function, which are present at birth. Major birth defects are abnormalities that lead to developmental or physical disabilities or require medical or surgical treatment and they're the leading cause of death in the first year of life. The objective of this study is to find the incidence of congenital abnormalities in this institution. Methods: This was a prospective study conducted in Institute of Medicine, Maharajgunj Medical Campus, Tribhuwan University Teaching Hospital from 14th April 2015 to 11th Feb ,2016 . All the delivered babies in this hospital during the study period were included. All the birth cases of gross congenital fetal malformation were identified and carefully studied and were classified according to the International Classification of diseases (ICD-10). Results: Total number of congenital fetal malformation abnormalities (CMF) delivered during this period was 94 (1.13%) in total 8300 birth /7868 live birth. CMF were categorized as, Musculoskeletal - 25.55%, CNS - 17.02%, Gastrointestinal -13.33%, Renal 14.25%, Cardiac -10.63%, Respiratory -10.6%, craniofacial - 9.57%, Genitouriary - 8.51%, and Miscellaneous - 9.57%. Conclusion: Birth abnormalities incompatible to life needs to be timely diagnosed and terminated, whereas as those compatible to life should be given a chance to be born and cared thereafter. All the mothers who have, had previous malformed babies must undergo preconceptional counseling, before planning next pregnancy in order to avoid recurrent mishap.

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Congenital malformations at birth in 7,922 consecutive deliveries at Patan Hospital, Nepal

Cited by 7 publications

References 2 publications

Congenital anomalies in antenatal ultrasound scan at a tertiary care teaching hospital

Congenital anomalies in antenatal ultrasound scan at a tertiary care teaching hospital

Prevalence of Congenital Malformations among Babies Delivered at a Tertiary Care Hospital

Incidence of Congenital Fetal Malformation Abnormalities in Tribhuban University, Teaching Hospital, Kathmandu, Nepal: a Hospital Based Study

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