Congenital Leukaemia

Abstract

Congenital letikaemia is a rare condition hut is often characterized hy multiple cutaneous sf<in infiltrates. A case is discussed and the literature is reviewed with particular reference to patho^ienesis, clinical presentation, investigations and differentialThe prognosis for survival may improve with early diagnosis and treatinent.conditions. Congenital leukaemia of the myeiogenous typo is nine titnes more common than lymphatic leukaemia.'

Congenital leukaemia: the Dutch experience and review of the literature

“…A Medline search for English language papers on congenital and neonatal leukaemia between 1975 and 2000 was carried out. A total of 102 patients with congenital leukaemia, as defined by the diagnostic criteria stated above, were identified (Abe et al , 1983; Allan et al , 1989; Badhe & Sane, 1992; Bastard et al , 1985; Benedict et al , 1979; Bernstein et al , 1984; Bernstein et al , 1987; Brissette et al , 1996; Campbell et al , 1997; Carney et al , 1992; Chu et al , 1983; Clark et al , 1984; Dinulos et al , 1997; Djernes et al , 1976; Embon et al , 1995; Fernandez et al , 1999; Francis et al , 1989; Fugazza et al , 1992; Gale & Toledano, 1984; Gale et al , 1986; Garewal et al , 1993; Gilgenkrantz et al , 1983; Gottesfeld et al , 1989; Gray et al , 1986; Hagemeijer et al , 1981; Hanada et al , 1991; Hara et al , 1984; Hayashi et al , 1985; Hazani et al , 1993; Heikinheimo et al , 1994; Huret et al , 1993; Irwin & Campbell, 1978; Isaacs, 1987; Jadhav et al , 1988; Kojima et al , 1989; Kurosawa et al , 1987; Kushwaha et al , 1977; Lampkin et al , 1985; Las‐Heras et al , 1986; Lasson & Goos, 1981; Liang et al , 1986; Liang et al , 1993; Lilleyman, 1980; Matamoros et al , 1994; Mayer et al , 1995; McCoy et al , 1995; Monpoux et al , 1996; Mori et al , 1997; Muchi et al , 1985; Odom & Gordon, 1984; Ohyashiki et al , 1988; Raney et al , 1979; Rechavi et al , 1988; Resnik & Brod, 1993; Ridge et al , 1995; Sainati et al , 1996; Sait et al , 1988; Seo et al , 1986; Shah et al , 1984; Shimizu et al , 1987; Shimizu et al , 1989; Shitara et al , 1992; Silberstein et al , 1979; Simon et al , 1984; Sippe, 1981; Spier et al ...…”