Congenital Intraocular Teratoma

Kivelä, Tero; Merenmies, Lauri; Ilveskoski, Ismo; Tarkkanen, Ahti

doi:10.1016/s0161-6420(93)31575-7

Cited by 15 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3 A literature review reveals only three previous case reports of intraocular teratomas. [4][5][6] Given the rarity of teratomas occurring in the eye, more common intraocular neoplasms must be excluded prior to arriving at the diagnosis. Retinoblastoma, the most common pediatric intraocular neoplasm, is composed of small round blue cells and has a vastly different histologic appearance than our tumor.…”

Section: Discussionmentioning

confidence: 99%

“…Of the three previous case reports of intraocular teratomas, two were congenital. Kivela et al 4 described an intraocular teratoma protruding from the orbit present at birth. Leventer et al 5 described a healthy baby girl born with an intraocular teratoma filling the left globe, with an associated lower lid coloboma.…”

Section: Discussionmentioning

confidence: 99%

“…Extragonadal germ cell tumors are thought to arise from germ cell precursors that become arrested during embryologic migration. 2 Kivela et al 4 theorize that the intraocular teratoma occurs through entrapment of germ cells within the eye by the invaginating optic cup. In our case, with fetal MRI showing a SCT and no demonstrable eye pathology, it is unclear whether the intraocular tumor is directly related to the sacrococcygeal teratoma or if a separate developmental event is responsible.…”

Section: Discussionmentioning

confidence: 99%

“…Kivela et al. 4 described an intraocular teratoma protruding from the orbit present at birth. Leventer et al.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Pediatric Intraocular Immature Teratoma Associated With Sacrococcygeal Teratoma

et al. 2017

View full text Add to dashboard Cite

Intraocular teratomas are rare neoplasms with only three previously reported cases. We present the fourth case of intraocular teratoma and the second associated with sacrococcygeal teratoma. While the nature of the association between intraocular teratomas and sacrococcygeal teratomas is unclear, it suggests a need for careful ophthalmologic follow-up of infants with congenital sacrococcygeal teratomas.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Kivela et al. 4 described an intraocular teratoma protruding from the orbit present at birth. Leventer et al.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Pediatric Intraocular Immature Teratoma Associated With Sacrococcygeal Teratoma

et al. 2017

View full text Add to dashboard Cite

show abstract

“…In the reported case, the initial diagnosis was intraocular teratoma. There are, however, only two cases of intraocular teratoma reported in the literature, both diagnosed in newborns (Kivelä et al 1993; Leventer et al 2001). Doubts about the diagnosis of teratoma and the unsatisfactory response to chemotherapy led us to revise the pathological diagnosis to malignant teratoid medulloepithelioma.…”

Section: Discussionmentioning

confidence: 99%

Intraocular malignant teratoid medulloepithelioma in an adult: clinicopathological case report and review of the literature

Sosińska-Mielcarek¹,

Senkus²,

Jaskiewicz³

et al. 2006

Acta Ophthalmologica Scandinavica

View full text Add to dashboard Cite

ABSTRACT.Purpose: To report a case of intraocular medulloepithelioma, an embryonal tumour with extremely rare presentation in adults. Method: The case of a 44-year-old man with intraocular malignant teratoid medulloepithelioma, primarily diagnosed as intraocular teratoma, is described and the literature on this subject is reviewed. Results: The patient presented with progressive proptosis caused by a tumour in the left eyeball. He had a 28-year history of loss of vision in the left eye. Histopathological examination of the enucleated eye demonstrated an intraocular teratoma. No adjuvant treatment was given. Six months later the patient presented with massive progression in the left orbit and intracranial invasion. Cisplatin-based chemotherapy was administered, but discontinued after two cycles due to poor tolerance and lack of response. At subsequent pathology review, a final diagnosis of malignant teratoid medulloepithelioma was made. Salvage radiotherapy (60 Gy in 30 fractions) resulted in partial response of the intracranial lesion. However, the patient died 6 months later due to intracranial tumour progression. Conclusion: Medulloepithelioma should be considered in the differential diagnosis of intraocular tumours in adults, especially in the case of coexisting, longstanding ocular symptoms. In some cases this disease is very aggressive.

show abstract

Intraocular Tumours

Roberts

Thum

2013

Lee's Ophthalmic Histopathology

View full text Add to dashboard Cite

Congenital Intraocular Teratoma

Cited by 15 publications

References 24 publications

Pediatric Intraocular Immature Teratoma Associated With Sacrococcygeal Teratoma

Pediatric Intraocular Immature Teratoma Associated With Sacrococcygeal Teratoma

Intraocular malignant teratoid medulloepithelioma in an adult: clinicopathological case report and review of the literature

Intraocular Tumours

Contact Info

Product

Resources

About