Congenital Heart Disease

Postoperative Cerebral Oxygen Saturation in Children After Congenital Cardiac Surgery and Long-Term Total Intelligence Quotient: A Prospective Observational Study

“…In this study, increased dose of Sct o 2 desaturation and lower mean Sct o 2 in the first 12 and 24 hours of monitoring independently increased the probability of having a lower total IQ 2 years after PICU admission. These findings are in line with previous studies that showed high vulnerability of the immature brain to prolonged periods of cerebral desaturation ( 2 , 3 , 7 , 13 , 29 – 31 ).…”

“…H alf of all children with congenital heart disease (CHD) undergo surgery in the first months of life (1,2). Despite high survival rates, many of the surviving children can suffer from long-term neurodevelopmental deficits (3)(4)(5)(6), as a result of white matter lesions following hypoxic or ischemic events (2,3,7,8). To maximize outcomes, the treating team pursue adequate oxygen delivery during the entire perioperative period.…”