Congenital diaphragmatic hernia: does gestational age at diagnosis matter when evaluating morbidity and mortality?

Epidemiology and Prognosis of Congenital Diaphragmatic Hernia: A Population‐Based Cohort Study in Utah

“…In other population‐based studies, mortality was similar (36%) in Sweden (Burgos and Frenckner, ), but much higher (66.9%) in Croatia (Grizelj et al, 2016). Among isolated CDH cases, Bouchghoul et al () reported a 6‐month mortality of 39% in France, which is much higher in our study (21.3% at 1 year). The reason for these differences is unclear.…”

Congenital diaphragmatic hernia has a better prognosis when associated with a hernia sac

“…Congenital diaphragmatic hernia with a hernia sac is a particular anatomical entity, and as the prognosis is improved, we can speculate that the diaphragmatic anomaly occurs at a later embryological stage of development, although in our study, the gestational age at diagnosis was similar in the 2 groups …”

“…Congenital diaphragmatic hernia with a hernia sac is a particular anatomical entity, and as the prognosis is improved, we can speculate that the diaphragmatic anomaly occurs at a later embryological stage of development, although in our study, the gestational age at diagnosis was similar in the 2 groups. 21 The strengths of our study include prospective data collection and similar postnatal management, as the study was conducted at a single center. Study limitations include sample size and the exclusion of 10 neonates who died before surgical repair and for whom no autopsy was performed.…”

Fetal stomach and gallbladder in contact with the bladder wall is a common ultrasound sign of stomach‐down left congenital diaphragmatic hernia

“…CDH is a diagnosis with potentially significant perinatal morbidity and mortality and has a high association with other fetal malformations. [6][7][8][9][10][11][12] It is therefore important to diagnose it as early as possible because of its impact on the management of the fetus, [13][14][15][16] including the assessment for other abnormalities and informed decision-making and planning for the expectant parents. 17 CDH can be difficult to detect early in the second trimester, 16 particularly when the stomach is below the diaphragm and only the small bowel is present in the chest.…”