Congenital cutaneous melanoma in a dog

Meyrer, Bruna; Bianchi, Simone Passos; Pavarini, Saulo Petinatti; Gerardi, Daniel Guimarães

doi:10.1111/vde.12391

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…Congenital cutaneous melanocytomas have been reported in cattle,7 horses,8 pigs9 10 and dogs 11. Congenital melanomas with evidence of invasion or metastasis are rare; they have been reported in cattle,12 horses,13 pigs,14 15 sheep,16 17 dogs18 and people 19. While the majority of congenital melanocytic tumours in people and domestic animals are cutaneous in origin, primary melanomas within the vertebral canal and calvarium have been reported in pigs14 15 and sheep 16 17.…”

Section: Discussionmentioning

confidence: 99%

Congenital intradural melanoma surrounding the spinal cord of a nine‐day‐old Saanen goat

Sinnott

Woolard

Heller

et al. 2020

Vet Record Case Reports

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A nine-day-old Saanen kid presented for progressive hind limb paresis since birth. Euthanasia was elected, and on postmortem examination a large, pigmented mass was present in the vertebral canal surrounding the lumbosacral and caudal thoracic spinal cord. Histopathology revealed a homogeneous population of round to spindle neoplastic cells containing finely granular pigment consistent with a melanoma. This diagnosis was further supported by a Fontana-Masson stain and immunohistochemistry for PNL2, MelanA and SOX10. The tumour presumably arose from melanocytes or melanocytic precursors within the meninges of the lumbosacral spinal cord. No evidence of neoplasia was seen elsewhere in the body; therefore, the meningeal melanoma likely represents the primary tumour. Goats develop neoplasms less frequently than other species, and reports of congenital tumours in goats are rare.

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