Congenital cutaneous candidiasis and candidemia in a preterm infant: A case report

Oberhauser, Sarah; Böhm, Sebastian; Niederer, A; Rogdo, Bjarte

doi:10.5430/crcp.v4n1p68

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Treatment and Outcome1

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2021

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“…The infant developed systemic candidiasis refractory to liposomal Amphotericin B and was treated with echinocandin Caspofungin, which led to prompt eradication of C. albicans fungemia without serious side effects. Oberhauser et al also reported positive results in treating refractory candidemia with echinocandin Micafungin [32].…”

Section: Treatment and Outcomementioning

confidence: 97%

Congenital systemic candidiasis: a comprehensive literature review and meta-analysis of 44 cases

Georgescu

Lisievici

Munteanu³

et al. 2021

Rom J Morphol Embryol

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Systemic candidiasis is a frequent complication in neonatal units, but congenital systemic candidiasis is an unusual diagnosis, observed in both full-term and preterm infants, with less than 50 cases reported to date. Congenital candidiasis presents with a wide spectrum of symptoms, ranging from diffuse skin eruptions to severe systemic disease, resulting in fetal demise or early neonatal death. Although management guidelines have been published almost two decades ago, due to the rarity of this type of infection, conclusive recommendations are difficult to establish, since they are based on anecdotal experience. In this paper, we present a comprehensive meta-analysis of the current scientific knowledge regarding congenital candidiasis, which spans 54 years and includes a total of 44 cases.

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Section: Treatment and Outcomementioning

confidence: 97%