2009
DOI: 10.1111/j.1540-8159.2009.02387.x
|View full text |Cite
|
Sign up to set email alerts
|

Congenital Coronary Artery Abnormalities Predisposing to Sudden Cardiac Death

Abstract: Isolated congenital coronary artery anomalies (CCAAs) are a rare but well-described cause of sudden cardiac death (SCD). Anomalous origin of a coronary artery from the opposite sinus has been most frequently associated with myocardial ischemia, ventricular arrhythmias, and sudden death, particularly when the anomalous coronary courses between the great arteries. Importantly, symptoms occur in only about 50% of people with CCAA who subsequently have SCD. Echocardiography is effective in prospectively identifyin… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
15
0

Year Published

2012
2012
2021
2021

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 35 publications
(15 citation statements)
references
References 41 publications
(91 reference statements)
0
15
0
Order By: Relevance
“…48 Clinical symptoms, such as exertional chest discomfort or dyspnea, may be helpful, but 2 reports suggest that 50% of SCDs associated with coronary artery anomalies were first events without prior symptoms. 46,49 The best methods for identifying the anomaly include coronary angiography, computed tomography angiography, and magnetic resonance angiography. Although not uniformly successful, athletes undergoing echocardiographic studies for any reason should have careful attempts to identify the origins of the coronary arteries.…”
Section: Congenital Coronary Anomaliesmentioning
confidence: 99%
“…48 Clinical symptoms, such as exertional chest discomfort or dyspnea, may be helpful, but 2 reports suggest that 50% of SCDs associated with coronary artery anomalies were first events without prior symptoms. 46,49 The best methods for identifying the anomaly include coronary angiography, computed tomography angiography, and magnetic resonance angiography. Although not uniformly successful, athletes undergoing echocardiographic studies for any reason should have careful attempts to identify the origins of the coronary arteries.…”
Section: Congenital Coronary Anomaliesmentioning
confidence: 99%
“…61,62 The most frequent anatomic findings consist of both (left and right) coronary arteries arising either from the right or the left coronary sinus. In both conditions, as the anomalous coronary vessel leaves the aorta, it adopts an acute angle with the aortic wall, and, thus, traverses between the aorta and the pulmonary trunk, often following an aortic intramural course, with a slit-like lumen.…”
Section: Congenital Coronary Artery Anomaliesmentioning
confidence: 99%
“…The effect of such abnormalities are diverse, ranging from insignificance to a predisposition to clot formation, atherosclerosis or spasm,75 76 to severe disruption in myocardial perfusion and critical ischaemia. In patients younger than 35 years, coronary artery anomalies are responsible for 17% of SCDs which occur in competitive athletes 77. A particularly severe abnormality is an aberrant origin of the left main stem coronary artery (originating from the right sinus of Valsalva) requiring the left main coronary artery to traverse behind or within the wall of the aorta.53 This can result in ischaemia or arrhythmia, particularly during periods of increased cardiac output, due to decreased coronary blood flow from either abnormal orientation of the vessel, or by external compression.…”
Section: Angina and Stable Cadmentioning
confidence: 99%