“…Secondary infections and inflammation can occur. Although unusual, bilateral second branchial cleft cysts have been reported and in some patients this is part of the branchio-oto-renal syndrome, an autosomal dominant disorder [1]. Mapped to chromosome 8q 13.3, other symptoms include hearing impairment, cup-shaped pinnae, preauricular pits, branchial fistulae and renal anomalies.…”