Congenital Candidiasis

Abstract

Congenital candidiasis presents with a variety of clinical features. We report two neonates with congenital candidiasis characterized by diffuse erythematous papules associated with pneumonia and respiratory distress. Candida pseudohyphae were identifiable in skin scrapings. Systemic cultures were negative, but urine and sputum cultures grew Candida albicans. After prompt systemic antifungal therapy, the infants were discharged from hospital with no overt complications. This report highlights the presence of characteristic skin lesions associated with candidal infection, occurring within 24 hours of birth. This is an important observation which could help in the early diagnosis of congenital candidal infection.

Congenital Systemic Fungus Infection in Twin Prematurity—A Case Report and Literature Review

“…in a newborn. 9 10 Although hematogenous route has been reported, 6 11 generally, it is an ascending infection from vagina resulting in chorioamnionitis. The infected amniotic fluid results in cutaneous candidiasis of fetus via direct contact and invades the body through the amniotic fluid circulation pathway.…”

Congenital Cutaneous Candidiasis in a Premature Neonate. Case Report

“…Every CCC approach should begin with clinical suspicion. However, a definite diagnosis, including microscopic evaluation, and the culture of Sabouraud dextrose agar from the mucocutaneous lesions, placenta, or umbilical cord, should be assessed [5][6][7][8] . The clinical course is benign and auto-limited.…”

ADN de Chlamydia trachomatis en leucocitos de sangre periférica de neonatos

“…Las infecciones respiratorias pueden ser producidas por otras bacterias o levaduras diferentes a Chlamydia o Mycoplasma; en esta investigación todos los cultivos microbiológicos de los aspirados bronquiales fueron negativos, excepto en un paciente, que mostró Candida albicans; esta levadura pudo haberse adquirido de manera congénita, aunque este neonato no presentó manifestaciones clínicas en la piel, por lo que esta infección se consideró de adquisición nosocomial 36,37 .…”