Ultrasound is now an integral part of any gynecological assessment. Using ultrasound, most gynecological conditions are diagnosed much easier and with great accuracy during a single outpatient visit. The introduction of three-dimensional (3D) ultrasound has the potential of creating a huge impact on the management of gynecological patients. To make the maximum benefit of this modality, the clinicians need to be trained on how to utilize this technique and should be made aware of all the potential uses and capabilities of the machines' software, which are built in the relatively new technology of 3D. In this review article, we discuss how to obtain optimum 3D images and some of the possible clinical applications of this technique. We also discuss in more detail the three major steps in obtaining 3D images, which are volume acquisition, volume display, and volume analysis.