Congenital anomalies in Santa Catarina: case distribution and trends in 2010–2018

Abstract

Objective: To evaluate the distribution of cases of congenital anomalies in the state of Santa Catarina by health macro-region, to determine the frequency according to maternal and neonatal variables, to estimate the related mortality, and the trends in the period 2010–2018. Methods: An ecological time-series study with secondary data on congenital anomalies and the sociodemographic and health variables of mothers and newborns living in Santa Catarina, from 2010 to 2018. For temporal trend analysis, generalized linear regression was performed using the Prais-Winsten method with robust variance. Results: The average prevalence of congenital anomalies in the period was 8.9 cases per 1,000 live births, being 9.4 cases by 1,000 live births in 2010 and, in 2018, 8.2/1,000. The trend remained stable in the analyzed period. The major malformations were musculoskeletal, hip, and foot malformations, with a proportion ≥30%. There was a higher prevalence of congenital anomalies in low birthweight, preterm, male livebirths with Apgar≤7, born by cesarean section, mothers of older age (≥40 years), and less educated (less than eight years of study). Infant mortality due to congenital malformations was 2.6 deaths/1,000 live births, representing about 25.8% of the total infant deaths in the period. Conclusions: The frequency of congenital anomalies and the mortality with anomalies was stable in the studied period in Santa Catarina. The presence of anomalies was associated with low birth weight, prematurity, and low Apgar score. The highest proportion of congenital anomalies was in the musculoskeletal system.

Prevalence of Congenital Anomaly and Its Relationship with Maternal Education and Age According to Local Development in the Extreme South of Brazil

“…Similarly, a study that evaluated national data from Argentina stratifying by public and private hospitals showed that, at the national level, the highest prevalence was observed in public hospitals compared to private ones [28]. Otherwise, many CA are identified during pregnancy, which may be linked to the high number of cesarean sections performed in this population, as has been shown in the literature [1,24,37].…”

Analysis of under-five mortality by diseases in countries with different levels of development: a comparative analysis

“…Results showed that CAs and prematurity were associated diseases, BABT were associated with OCPNC and non-communicable in U5CM in developed countries. In the literature, it has been shown there is a correlation between CAs and preterm birth [36]. Prematurity, CAs, BABT and OCPNC are in same group in Australia and Canada.…”

Prevalência de anomalias congênitas no brasil: 2017-2020

“…No que se refere à escolaridade materna, observou-se maior prevalência de anomalias congênitas em mães com nenhuma escolaridade. Assim, a maior taxa de malformações nesta população relaciona-se, em geral, à dificuldade de acesso a informação e atendimento pré-natal adequado, bem como maior chance de exposição a carências nutricionais e demais substâncias nocivas ao feto 25,26,30 .…”

“…Neste estudo, foi observado maior prevalência de parto cesáreo antes do trabalho de parto nos casos de anomalias congênitas, fato associado ao diagnóstico da malformação intraútero e, consequente realização de cesárea por opção médica, indicado em algumas situações de alto risco 25,26,27 . Entretanto, sabemos que a presença de alterações congênitas não é indicação absoluta de cesárea.…”